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- Table of Contents
Facts about ETS domain-containing transcription factor ERF.
Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). Might be important for regulating trophoblast stem cell differentiation (By similarity).
Human | |
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Gene Name: | ERF |
Uniprot: | P50548 |
Entrez: | 2077 |
Belongs to: |
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ETS family |
Ets2 repressor factorPE-2PE2ETS domain-containing transcription factor ERF
Mass (kDA):
58.703 kDA
Human | |
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Location: | 19q13.2 |
Sequence: | 19; NC_000019.10 (42247561..42255128, complement) |
Highest levels in testis, ovary, pancreas, and heart.
Nucleus.
PMID: 7588608 by Sgouras D.N., et al. ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation.
PMID: 9192842 by de Castro C.M., et al. Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF).