GTPase Era, mitochondrial Antibodies

AND ERAL1 ELISA kits, GTPase Era, mitochondrial Proteins

Many biological assays use antibodies to detect GTPase Era, mitochondrial, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GTPase Era, mitochondrial in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GTPase Era, mitochondrial antibodies...

We validate the specificity of these antibodies to GTPase Era, mitochondrial by testing them on tissues known to express ERAL1 positively and negatively. Browse below to find the ERAL1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ERAL1 Infographic by Boster Bio

All ERAL1 Products

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Anti-GTPase Era, mitochondrial ERAL1 Antibody

Human, Mouse, Rat

$405
Cat # A11370
100ul

GTP binding protein era homolog (ERAL1) (NM_005702) Human Over-expression Lysate

Human

$628
Cat # LS026284
100 µg

ERAL1 Overview

Facts about GTPase Era, mitochondrial.

ERAL1 3D structure. Source: alphafold

GTPase Era, mitochondrial (ERAL1)

Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region.

May act as a chaperone that shields the 12S mt-rRNA on the 28S mitoribosomal subunit through ribosomal small subunit assembly. .

Gene Information

Human
Gene Name:	ERAL1
Uniprot:	O75616
Entrez:	26284

Family

Belongs to:

TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily

Alternative Names

CEGA; Conserved ERA-like GTPase; Era (E. coli G-protein homolog)-like 1; Era G-protein-like 1 (E. coli); ERA; ERAL1A; ERA-like protein 1; ERA-W; GTPase Era, mitochondrial; GTPase, human homolog of E. coli essential cell cycle protein Era; GTP-binding protein era homolog; hERA; H-ERA; HERA-A; HERA-B

Molecular Weight

Mass (kDA):
48.35 kDA

Genomic Context


Human

Location:	17q11.2
Sequence:	17; NC_000017.11 (28855016..28861061)

Subcellular Localizations

Mitochondrion matrix. Mitochondrion inner membrane; Peripheral membrane protein. Localizes on the matrix side on the mitochondrial inner membrane.

Diseases

Malignant Neoplasms
Growth Retardation
Malignant Neoplasm Of Prostate
Neoplasms

Interacting Proteins

CEP44

Pathways

Cell Division
Translation
Mitochondrial Translation
Localization
Cell Cycle
Cellular Localization
Cell Death

Ribosome Assembly
Chromosome Segregation

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ERAL1

References

PMID: 10945472 by Britton R.A., et al. Isolation and preliminary characterization of the human and mouse homologues of the bacterial cell cycle gene era.

PMID: 11733036 by Akiyama T., et al. Mammalian homologue of E. coli Ras-like GTPase (ERA) is a possible apoptosis regulator with RNA binding activity.