Claudin-17 Antibodies

AND CLDN17 ELISA kits, Claudin-17 Proteins

Many biological assays use antibodies to detect Claudin-17, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Claudin-17 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Claudin-17 antibodies...

We validate the specificity of these antibodies to Claudin-17 by testing them on tissues known to express CLDN17 positively and negatively. Browse below to find the CLDN17 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CLDN17 Infographic by Boster Bio

All CLDN17 Products

Product

Figures

Specificity

Applications

Price

Anti-Claudin-17 CLDN17 Antibody

Human

ELISA, WB

$380
Cat # A14487
100ul

Claudin 17 (CLDN17) (NM_012131) Human Over-expression Lysate

Human

$628
Cat # LS026285
100 µg

CLDN17 Overview

Facts about Claudin-17.

CLDN17 3D structure. Source: alphafold

Claudin-17 (CLDN17)

Channel-forming tight junction protein with selectivity for anions, such as chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. From the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions.

Does not affect water permeability. .

Gene Information

Human
Gene Name:	CLDN17
Uniprot:	P56750
Entrez:	26285

Family

Belongs to:

claudin family

Alternative Names

claudin 17; Claudin17; Claudin-17; CLDN17; human CLDN17 gene for claudin-17, 10claudin-17; MGC126552; MGC126554

Molecular Weight

Mass (kDA):
24.603 kDA

Genomic Context


Human

Location:	21q21.3
Sequence:	21; NC_000021.9 (30165565..30166805, complement)

Tissue Specificity

In the kidney, expressed in the proximal tubule and in the Henle's loop. In the distal convoluted tubule, not expressed in all tubules. Not detected in the collecting duct (at protein level).

Subcellular Localizations

Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Stomach Neoplasms
Malignant Neoplasm Of Breast
Hepatitis
Colonic Neoplasms
Malignant Paraganglionic Neoplasm
Hepatitis C
Carcinoma

Invasive Ductal Breast Carcinoma
Malignant Neoplasm Of Stomach
Mammary Neoplasms
Ductal Breast Carcinoma

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLDN17

References

PMID: 20375010 by Harris H.J., et al. Claudin association with CD81 defines hepatitis C virus entry.

PMID: 22402829 by Krug S.M., et al. Claudin-17 forms tight junction channels with distinct anion selectivity.