Ephrin type-A receptor 3 Antibodies

Ephrin type-A receptor 3 (EPHA3)

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is known as forward signaling while the signaling pathway downstream of the ephrin ligand is known as reverse signaling.

Upon activation by EFNA5 modulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1.

Gene Information

Human
Gene Name:	EPHA3
Uniprot:	P29320
Entrez:	2042

Family

Belongs to:
protein kinase superfamily

Alternative Names

Cek4; EC 2.7.10; EC 2.7.10.1; EK4; EPH receptor A3; EphA3; EPH-like kinase 4; ephrin type-A receptor 3; ETK; Hek4; HEKETK1eph-like tyrosine kinase 1; human embryo kinase 1; TYRO4 protein tyrosine kinase; Tyro4; Tyrosine-protein kinase receptor ETK1; Tyrosine-protein kinase TYRO4

Molecular Weight

Mass (kDA):
110.131 kDA

Genomic Context

Human
Location:	3p11.1
Sequence:	3; NC_000003.12 (89107621..89482134)

Tissue Specificity

Widely expressed. Highest level in placenta.

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.

Diseases

• Malignant Neoplasms
• Neoplasms
• Tissue Adhesions
• Carcinoma
• Neoplasm Metastasis
• Cell Transformation, Neoplastic
• Melanoma
• Colorectal Cancer
• Nervousness
• Tumor Angiogenesis
• Adenocarcinoma
• Optic Nerve Injuries

• Malignant Squamous Cell Neoplasm
• Lung Neoplasms
• Leukemia
• Prostatic Neoplasms
• Tumor Progression
• Malignant Neoplasm Of Prostate
• Spinal Cord Injuries

Pathways

• Cell Adhesion
• Cell Migration
• Regeneration
• Axon Guidance
• Localization
• Methylation
• Angiogenesis
• Innervation
• Cell Growth
• Inflammatory Response
• Cell Motility
• Cell-cell Adhesion
• Oncogenesis

• Cell Proliferation
• Dna Methylation
• Tissue Regeneration
• Cell Death
• Neural Tube Closure
• Dna Hypermethylation
• Cellular Senescence

PTMs

• Phosphorylation
• Methylation

• Cleavage
• Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EPHA3

Best Uses Of The EPHA3 Marker

You've found the right place if you're looking to find a biomarker that can be used to assess the health of your blood. There are many types of biomarkers available, including the EPHA3 marker. This article will explain the differences and how to get the best from each of these markers. You will also learn how to interpret EPHA3 results in relation to your health.

TEM1

EPHA3 is an EPHA3 protein that is found in many organisms. This includes humans, bacteria and fungi. Researchers using the marker to examine vascular and immune system disorders can see if their patients respond to the drug. The EPHA3 markers were shown to improve the efficacy of an ENCA-type heart failure drug.

TEM2

Knowing your options is key if you want to learn more about the EphA3 marking. A boster bio antibody is one option. This boster bio antibody reacts to EphA3 proteins from Rat, Mouse, and Human. There are a few ways you can use this antibody, but the most important thing to remember is that it should be used in conjunction with other Boster bio products.

TEM3

Boster Bio offers high-affinity EphA3 antibodies. This will ensure the best results. These antibodies have been well-cited and are trusted by the research community. The manufacturer of this product has verified its high-affinity antibodies by using Western Blotting, Immunohistochemistry, and ELISA. This antibody is ideal if you need high-affinity antibodies to detect EPHA3 from target cells in research studies.

TEM4

These biologically active fragments of EPHA3 are available for use in the current methods and compositions. These fragments are composed of a part of the encoding DNA sequence and retain the biological activities of the full-length protein. These fragments have the same function, and the present methods and compositions can be used to evaluate their immunogenicity. Boster Bio offers several adenoviruses that may provide the best results.

Recombinant genomic technology can be used for the design of TVM polypeptides, analogs, and other molecules. Recombinant genetic technology may allow for the creation of novel mutant proteins. They can be modified with single or multiple amino acids substitutions, additions, or deletions. These proteins can have higher activity and stability and may be more easily purified than natural polypeptides. Molecular markers are useful for evaluating the effectiveness of biological interventions in a variety of research fields.

TEM 5

The Boster Bio Anti-Ephrin-A-receptor 3 EphA3 Antibody is a mouse-specific monoclonal antibody. The antibody reacts with Humans, Rats, and Mice. The Boster Anti-Ephrin-A-receptor 3 EphA3 Antibody is available for purchase at bosterbio.com.

TEM 6

EPHA3 is a protein expressed in E. coli. Boster Biologics EPHA3 Monoclonal antibody is its primary antibody. It reacts to both human and eukaryotic tissues. It is stable at -20degC for up to a year and can be stored at 4degC for up to a month. The monoclonal, polyclonal monoclonal antibodies react with the EphA3 EPHA4 fraction. This fragment is expressed in E. Coli. It contains aa751-983.

TEM 7

The EPHA3 marker is a widely used protein found in various cells. It is used by scientists to monitor the levels of cell-surface oils in the body. Boster offers high-affinity primary antibodies, which have been extensively validated on Western Blotting, Immunohistochemistry, and ELISA methods. EPHA3 is expressed in the intestinal lining of E. coli bacteria.

TEM 8

One of the most important things you should remember when researching the best methods to analyze a target proteins is that there are many options. No matter what your research focuses on, there is a marker that will work. If you're unsure how to use this particular marker, read on to find the best method for your particular application.

TEM 9

The EPHA3 marker can be used to detect EphA3, which is a protein found in E. coli. This protein is essential in the immune system and can be used to detect a variety diseases. Scientists can submit results from a variety of samples, including applications and species. These scientists can also be eligible for product credits. The best part of these credits is that they are available to all scientists in the world.

TEM 11

The EPHA3 gene marker can be used to conduct biomedical studies. It can be used for biomarker purposes to distinguish human protein from those of other animal species. Boster also provides high-affinity primary antibody, which are highly cited and trusted by researchers. They are validated on a range of platforms, including Western Blotting, Immunohistochemistry, and ELISA.