Band 4.1-like protein 4B Antibodies

AND Epb41l4b ELISA kits, Band 4.1-like protein 4B Proteins

Many biological assays use antibodies to detect Band 4.1-like protein 4B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Band 4.1-like protein 4B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Band 4.1-like protein 4B antibodies...

We validate the specificity of these antibodies to Band 4.1-like protein 4B by testing them on tissues known to express Epb41l4b positively and negatively. Browse below to find the Epb41l4b antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Epb41l4b Infographic by Boster Bio

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EHM2 (EPB41L4B) (NM_018424) Human Over-expression Lysate

Human

$960
Cat # LS054566
100 µg

Epb41l4b Overview

Facts about Band 4.1-like protein 4B.

Band 4.1-like protein 4B (Epb41l4b)

Up-regulates the action of the Rho guanine nucleotide exchange factor ARHGEF18 (PubMed:22006950). Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950).

Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (By similarity). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (By similarity).

Gene Information

Mouse
Gene Name:	Epb41l4b
Uniprot:	Q9JMC8
Entrez:	54357

Family

Belongs to:

No superfamily

Alternative Names

band 4.1-like protein 4B; CG1; DKFZp761N1814; EHM2FLJ21596; erythrocyte membrane protein band 4.1 like 4B; FERM-containing protein CG1; Protein EHM2

Molecular Weight

Mass (kDA):
59.564 kDA

Genomic Context


Mouse

Location:	4 B3\|4 31.66 cM
Sequence:	4;

Tissue Specificity

Expressed in mouse liver cells, with lower amounts in lung, kidney and in 7- to 17-day embryos. Expression not detected in adult mouse heart, brain, spleen, skeletal muscle or testis.

Diseases

Tissue Adhesions
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Prostate
Neoplasm Metastasis
Prostatic Neoplasms
Neoplasm Invasiveness
Carcinoma
Cell Invasion
Adenocarcinoma
Janiceps
Metastatic Malignant Neoplasm To The Lymph Node

Malignant Neoplasm Of Breast
Bone Neoplasms
Respiration Disorders
Carcinogenesis
Osteosarcoma
Innate Immune Response
Mammary Neoplasms

Pathways

Cell Adhesion
Regulation Of Cell Cycle
Cell Proliferation
Dna Hypomethylation
Establishment Of Cell Polarity
Dna Methylation
Immune Response
Cell-matrix Adhesion
Synaptic Transmission
Dendritic Spine Morphogenesis

Methylation
Cell Cycle
Cell Motility
Innate Immune Response
Rna Interference

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Epb41l4b

References

PMID: 10783258 by Shimizu K., et al. Molecular cloning of a novel NF2/ERM/4.1 superfamily gene, Ehm2, that is expressed in high-metastatic K1735 murine melanoma cells.

PMID: 22006950 by Nakajima H., et al. Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF.