This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Eomesodermin homolog.
Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes.
Human | |
---|---|
Gene Name: | EOMES |
Uniprot: | O95936 |
Entrez: | 8320 |
Belongs to: |
---|
No superfamily |
EOMES; eomesodermin (Xenopus laevis) homolog; Eomesodermin; t box, brain, 2; T-box brain protein 2; T-box brain2; TBR2; TBR-2; TBR2eomesodermin homolog; T-brain-2
Mass (kDA):
72.732 kDA
Human | |
---|---|
Location: | 3p24.1 |
Sequence: | 3; NC_000003.12 (27715949..27722715, complement) |
Expressed in CD8+ T-cells.
Nucleus.
PMID: 10407135 by Kimura N., et al. A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain.
PMID: 18316326 by Nagase T., et al. Exploration of human ORFeome: high-throughput preparation of ORF clones and efficient characterization of their protein products.