Endonuclease V Antibodies

AND ENDOV ELISA kits, Endonuclease V Proteins

Many biological assays use antibodies to detect Endonuclease V, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endonuclease V in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endonuclease V antibodies...

We validate the specificity of these antibodies to Endonuclease V by testing them on tissues known to express ENDOV positively and negatively. Browse below to find the ENDOV antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ENDOV Infographic by Boster Bio

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Endonuclease V (ENDOV) (NM_173627) Human Over-expression Lysate

Human

$628
Cat # LS284131
100 µg

ENDOV Overview

Facts about Endonuclease V.

Endonuclease V (ENDOV)

Endoribonuclease that specifically cleaves inosine- containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Has strong taste for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs).

Cleaves mRNAs and tRNAs containing inosine. Also able to cleave structure-specific dsRNA substrates containing the particular sites 5'-IIUI-3' and 5'- UIUU-3'.

Gene Information

Human
Gene Name:	ENDOV
Uniprot:	Q8N8Q3
Entrez:	284131

Family

Belongs to:

endonuclease V family

Alternative Names

EC 3.1; hypothetical protein FLJ35220; hypothetical protein LOC284131; MGC74455

Molecular Weight

Mass (kDA):
30.792 kDA

Genomic Context


Human

Location:	17q25.3
Sequence:	17; NC_000017.11 (80415117..80438086)

Subcellular Localizations

Cytoplasm. Nucleus, nucleolus.

Diseases

Malignant Neoplasms
Neoplasms
Adenocarcinoma
Endometriosis, Site Unspecified
Intracranial Arteriovenous Malformation
Cell Transformation, Neoplastic
Headache
Colorectal Neoplasms
Chronic Inflammation

Von Hippel-lindau Syndrome
Inflammation
Arteriovenous Malformation

Pathways

Dna Repair
Methylation
Recombinational Repair
Dna Replication
Oncogenesis

PTMs

Deamination

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ENDOV

References

PMID: 22664237 by Mi R., et al. Human endonuclease V as a repair enzyme for DNA deamination.

PMID: 23139746 by Fladeby C., et al. The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures.