ENDOG Antibodies

AND ENDOG ELISA kits, ENDOG Proteins

Many biological assays use antibodies to detect ENDOG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ENDOG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ENDOG antibodies...

We validate the specificity of these antibodies to ENDOG by testing them on tissues known to express ENDOG positively and negatively. Browse below to find the ENDOG antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ENDOG Infographic by Boster Bio

All ENDOG Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-EndoG Monoclonal Antibody [7G1C10]

Human, Mouse, Rat

ELISA, WB

$524
Cat # M05147
0.1 mg

Anti-Endo G Antibody

Human

ICC, WB

$405
Cat # A05147-1
100ul

Anti-Endo G (ENDOG) Mouse Monoclonal Antibody [Clone ID: OTI5F1]

+11

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M05147-1
100 µl

Anti-Endo G Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M05147-2
100 μl/vial

Endo G (ENDOG) (NM_004435) Human Over-expression Lysate

Human

$628
Cat # LS002021
100 µg

ENDOG Overview

Facts about Endonuclease G, mitochondrial.

ENDOG 3D structure. Source: alphafold

Endonuclease G, mitochondrial (ENDOG)

Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts.

Along with deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of creating the RNA primers demanded by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).

Gene Information

Human
Gene Name:	ENDOG
Uniprot:	Q14249
Entrez:	2021

Family

Belongs to:

DNA/RNA non-specific endonuclease family

Alternative Names

EC 3.1.30.-; Endo G; endonuclease G; endonuclease G, mitochondrial; FLJ27463; mitochondrial endonuclease G

Molecular Weight

Mass (kDA):
32.62 kDA

Genomic Context


Human

Location:	9q34.11
Sequence:	9; NC_000009.12 (128818402..128822676)

Subcellular Localizations

Mitochondrion.

Diseases

Malignant Neoplasms
Carcinoma
Neoplasms
Ischemia
Atrophy
Dna Degradation, Apoptotic
Malignant Tumor Of Cervix
Hypoxia
Osteosarcoma
Edema
Cerebrovascular Accident
Malignant Squamous Cell Neoplasm
Muscular Atrophy

Leukemia
Melanoma
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Hypertrophy
Myocardial Ischemia
Nerve Degeneration

Interacting Proteins

DNAJA4

Pathways

Cell Death
Programmed Cell Death
Cell Proliferation
Localization
Cell Cycle
Rna Interference
Cell Cycle Arrest
Induction Of Apoptosis
Cell Killing
Muscle Atrophy
Apoptotic Process
Dna Recombination
Mating

Dna Replication
Apoptotic Dna Fragmentation
Autophagy
Secretion
Skeletal Muscle Atrophy
Transport
Cell Migration

PTMs

Cleavage
Phosphorylation
Deamination
Carbamylation

Acetylation
Oxidation
Methylation
Deglycosylation

Ubiquitination

Research Areas

Apoptosis
Cancer
Hypoxia

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ENDOG

References

PMID: 7789991 by Tiranti V., et al. Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis.