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- Table of Contents
Facts about Ectoderm-neural cortex protein 1.
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Human | |
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Gene Name: | ENC1 |
Uniprot: | O14682 |
Entrez: | 8507 |
Belongs to: |
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No superfamily |
CCL28; ectodermal-neural cortex 1 (with BTB-like domain); ENC-1BTB domain-like (brain); FLJ39259; PIG10KLHL35; tumor protein p53 inducible protein 10
Mass (kDA):
66.13 kDA
Human | |
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Location: | 5q13.3 |
Sequence: | 5; NC_000005.10 (74627406..74641424, complement) |
Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas. May be down- regulated in neuroblastoma tumors.
Nucleus matrix. Cytoplasm. Cytoplasm, cytoskeleton.
PMID: 9305847 by Polyak K., et al. A model for p53-induced apoptosis.
PMID: 9683534 by Hernandez M.-C., et al. Cloning of human ENC-1 and evaluation of its expression and regulation in nervous system tumors.