Protein enabled homolog Antibodies

Protein enabled homolog (Enah)

Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity like axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin wealthy outgrowths in fibroblasts.

Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation. .

Gene Information

Mouse
Gene Name:	Enah
Uniprot:	Q03173
Entrez:	13800

Family

Belongs to:
Ena/VASP family

Alternative Names

ENA; enabled homolog (Drosophila); ENAH; FLJ10773; Mena; MENANDPP1; NDPP1; protein enabled homolog

Molecular Weight

Mass (kDA):
85.844 kDA

Genomic Context

Mouse
Location:	1 H5|1 84.93 cM
Sequence:	1;

Tissue Specificity

Expressed in heart and testis, lower levels in lung, skeletal muscle, kidney, pancreas and brain. Isoform 5 is expressed exclusively in the brain. Isoform 2 is expressed predominantly in brain, testis, ovary and fat. In the brain, isoforms 2 and 5 are expressed at highest levels in the hippocampus, cortex and midbrain, and at lowest levels in the striatum and cerebellum. Isoform 6 is expressed in brain and spleen.

Diseases

• Tissue Adhesions
• Neoplasms
• Malignant Neoplasms
• Cell Invasion
• Neoplasm Metastasis
• Mammary Neoplasms
• Malignant Neoplasm Of Breast
• Carcinoma
• Neoplasm Invasiveness
• Protrusion
• Adenocarcinoma
• Carcinogenesis
• Metastatic Malignant Neoplasm To The Lung

• Tumor Progression
• Mammary Neoplasms, Experimental
• Ductal Carcinoma
• Ductal Breast Carcinoma
• Malignant Squamous Cell Neoplasm
• Lung Neoplasms
• Primary Neoplasm

Pathways

• Cell Motility
• Cell Migration
• Cell Adhesion
• Regulation Of Cell Motility
• Localization
• Axon Guidance
• Wound Healing
• Cell-cell Adhesion
• Cell Proliferation
• Rna Interference
• Immune Response
• Platelet Activation
• Platelet Aggregation

• Chemotaxis
• Cell Death
• Angiogenesis
• Pathogenesis
• Epithelial Cell-cell Adhesion
• Hyperphosphorylation
• Dorsal Closure

PTMs

• Phosphorylation

• Dephosphorylation

Research Areas

• Cancer
• Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Enah

Best Uses Of The ENAH Marker

When you are trying to find the best ENAH antibody, you should know that there are a lot of choices to make. This is true for almost every step of the experiment, from the sample preparation to the antibodies and blocking buffers. Boster Bio provides optimization tips and guides to help you get the most from your experiments. If you're not sure where to begin, you should consult these guides to learn the proper way to optimize your experiments.

Boster Bio optimization tips

The ELISA procedure involves making choices at nearly every step. From sample preparation to antibody concentration, there are many variables to consider. A boster Bio optimization guide can answer any questions you might have about this procedure. In addition to providing answers to common questions, the guide also addresses issues such as negative controls and isotype controls. Learn more about optimizing your experiment by reading the following Boster Bio optimization tips.

Boster's high-affinity primary antibodies

To determine whether a protein is inactivated or active in human tissues, researchers can use an anti-enamyl-alpha antibody (ANAA). ENAH antibodies are highly specific, highly cited antibodies that recognize and bind to the epitope of an adenosine triphosphate ring (Ala). These monoclonal and polyclonal antibodies can be used for research, diagnosis, and drug development.

The company's antibody portfolio includes more than 16,000 research antibodies validated for multiple assays. Its antibodies are optimized for ELISA and WB, and the company also offers a free secondary antibody with each purchase. The company also offers many kits and reagents for human and mouse samples. Its quality guarantee assures each product is as described. These reagents can be used by researchers in a variety of fields, including neuroscience, glycan analysis, and immunodiagnostic testing.

To determine whether a particular antibody is specific, the ENAH marker is used in combination with a primary antibody. The ENAH marker is highly specific for human ENAH, a protein that is present on most tissues. When used in combination with Boster's high-affinity primary antibodies, ENAH can detect as many as 61 different antigens in one tissue. In addition, complex digital analysis tools are now available.

Alper Biotech produces monoclonal antibodies and peptides for a variety of diagnostic and therapeutic applications. Its website features a large catalog of over 40,000 antibodies, including many of the most relevant, druggable targets. Alternatively, it provides antibody conjugates and customer services for the development of multiplex assays. There are also several companies that specialize in a specific area of research and development.

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