ELF4 Antibodies

AND ELF4 ELISA kits, ELF4 Proteins

Many biological assays use antibodies to detect ELF4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ELF4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ELF4 antibodies...

We validate the specificity of these antibodies to ELF4 by testing them on tissues known to express ELF4 positively and negatively. Browse below to find the ELF4 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ELF4 Infographic by Boster Bio

All ELF4 Products

Product

Figures

Specificity

Applications

Price

Anti-ELF4/Mef Antibody

Human

$360
Cat # A03714
100 µl

Anti-Elf-4 Antibody

7 Q&As

Human, Mouse

$399
Cat # A03714-1
100μl

Anti-Elf-4 Antibody

Human, Mouse, Rat

$405
Cat # A03714-2
100ul

Anti-ELF4 Mouse Monoclonal Antibody [Clone ID: OTI2D8]

Human

IHC, WB

$523
Cat # M03714
100 µl

ELF4 (NM_001421) Human Over-expression Lysate

Human

$628
Cat # LS002000
100 µg

ELF4 Overview

Facts about ETS-related transcription factor Elf-4.

ELF4 3D structure. Source: alphafold

ETS-related transcription factor Elf-4 (ELF4)

Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene.

Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells.

Gene Information

Human
Gene Name:	ELF4
Uniprot:	Q99607
Entrez:	2000

Family

Belongs to:

ETS family

Alternative Names

E74-like factor 4 (ets domain transcription factor); E74-like factor 4; ETS-related transcription factor Elf-4; MEFELFRMyeloid Elf-1-like factor

Molecular Weight

Mass (kDA):
70.73 kDA

Genomic Context


Human

Location:	Xq26.1
Sequence:	X; NC_000023.11 (130063955..130110891, complement)

Tissue Specificity

Abundantly expressed in the placenta and in a variety of myeloid leukemia cell lines. Moderate levels of expression in heart, lung, spleen, thymus, peripheral blood lymphocytes, ovary and colon. Lower levels of expression in Jurkat T-cells and other T-cell lines and no expression in brain.

Subcellular Localizations

Nucleus, PML body. Accumulation into PML nuclear bodies is mediated by PML.

Diseases

Neoplasms
Malignant Neoplasms
Leukemia
Myeloid Leukemia
Leukemia, Myelocytic, Acute
Cell Transformation, Neoplastic
Acute Promyelocytic Leukemia
Chromosomal Translocation
Sarcoma
Lymphoma
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Prostate

Somatotropin Deficiency
X-linked Agammaglobulinemia
Immunologic Deficiency Syndromes
Tumor Angiogenesis
(balanced Rearrangements Or Structural Markers Nec) Or (balanced Translocations)
Nasal Type Extranodal Nk/t-cell Lymphoma
Prostatic Neoplasms

Pathways

Translation
Cell Cycle
Cell Proliferation
Senescence
Cell Death
Circadian Rhythm
Pathogenesis
Cell Development
Localization
Osteoblast Differentiation
Cellular Senescence
Proteolysis
Cell Cycle Arrest

Oncogenesis
De-etiolation
Cell Growth
Angiogenesis
Bone Resorption
Autophagy
Cell Adhesion

PTMs

Phosphorylation
Sumoylation

Biotinylation
Glycosylation

Ubiquitination

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ELF4

References

PMID: 8895518 by Miyazaki Y., et al. MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties.

PMID: 9524226 by Aryee D.N.T., et al. Cloning of a novel human ELF-1-related ETS transcription factor, ELFR, its characterization and chromosomal assignment relative to ELF- 1.