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- Table of Contents
Facts about Eukaryotic translation initiation factor 4E transporter.
.
Human | |
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Gene Name: | EIF4ENIF1 |
Uniprot: | Q9NRA8 |
Entrez: | 56478 |
Belongs to: |
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No superfamily |
4E-TFLJ26551,2610509L04Rik; Clast4; eIF4E-transporter; eukaryotic translation initiation factor 4E nuclear import factor 1eIF4E transporter; eukaryotic translation initiation factor 4E transporter; FLJ21601
Mass (kDA):
108.201 kDA
Human | |
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Location: | 22q12.2 |
Sequence: | 22; NC_000022.11 (31434648..31489950, complement) |
Widely expressed.
Cytoplasm. Nucleus. Nucleus, PML body. Nucleus speckle. Predominantly cytoplasmic. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Localization to nuclear foci and speckles requires active transcription.
PMID: 10856257 by Dostie J., et al. A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E.
PMID: 16699599 by Wichroski M.J., et al. Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies.