Eukaryotic translation initiation factor 4E type 2 (EIF4E2)

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349). Acts as a repressor of translation initiation (PubMed:22751931).

Compared to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it functions by competing with EIF4E and block assembly of eIF4F in the cap (By similarity). .