EIF4B Antibodies

AND EIF4B ELISA kits, EIF4B Proteins

Many biological assays use antibodies to detect EIF4B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF4B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF4B antibodies...

We validate the specificity of these antibodies to EIF4B by testing them on tissues known to express EIF4B positively and negatively. Browse below to find the EIF4B antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF4B Infographic by Boster Bio

All EIF4B Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-eIF4B(Ab-422) Antibody

6 Q&As

Human, Mouse, Rat

IHC, WB

$360
Cat # A00846
100 µl

eIF4B Colorimetric Cell-Based ELISA Kit

Human, Mouse

ELISA

$480
Cat # EKC1187
1 kit, containing one 96-well plate and all necessary reagents

eIF4B (Phospho-Ser422) Colorimetric Cell-Based ELISA Kit

Human, Mouse

ELISA

$540
Cat # EKC2152
1 kit, containing two 96-well plates and all necessary reagents

Anti-eIF4B (phospho-Ser422) Antibody

Human, Mouse, Rat

$482
Cat # A00846S422
100ul

Anti-eIF4B (phospho-S422) Antibody

Human, Mouse, Rat

IF, IHC, WB

$482
Cat # A00846S422-1
100ul

Anti-EIF4B Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A00846-1
100 μg/vial

Anti-Phospho-eIF4B (S406) Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # P00846
100 μl/vial

EIF4B (NM_001417) Human Over-expression Lysate

Human

$628
Cat # LS001975
100 µg

EIF4B Overview

Facts about Eukaryotic translation initiation factor 4B.

EIF4B 3D structure. Source: alphafold

Eukaryotic translation initiation factor 4B (EIF4B)

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A.

Binds close to the 5'- terminal cap of mRNA in existence of EIF-4F and ATP. Promotes the ATPase activity as well as the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Gene Information

Human
Gene Name:	EIF4B
Uniprot:	P23588
Entrez:	1975

Family

Belongs to:

No superfamily

Alternative Names

Eif4a2; eIF4B; EIF-4B; eukaryotic translation initiation factor 4B; PRO1843

Molecular Weight

Mass (kDA):
69.151 kDA

Genomic Context


Human

Location:	12q13.13
Sequence:	12; NC_000012.12 (53006456..53042215)

Diseases

Foot-and-mouth Disease
Malignant Neoplasms
Neoplasms
Hepatitis
Hepatitis C
Carcinoma
Malignant Paraganglionic Neoplasm
Patient Dependence On
Tumor Angiogenesis
Precancerous Conditions
Adenocarcinoma
Aids-associated Nephropathy

Malignant Squamous Cell Neoplasm
Cell Transformation, Neoplastic
Picornaviridae Infections
Peritoneal Carcinomatosis
Stomach Neoplasms
Neoplasm Metastasis

Interacting Proteins

PLK1
TINF2

Pathways

Translation
Translational Initiation
Cell Growth
Cell Proliferation
Induction Of Apoptosis
Cell Death
Regulation Of Translation
Rna Interference
Transport
Cell Cycle
Angiogenesis
Hibernation
Programmed Cell Death

Pseudohyphal Growth
Stress Granule Assembly
Spermatogenesis
Cell Cycle Arrest
Cytokinesis
Glucose Homeostasis
Seed Development

PTMs

Phosphorylation
Cleavage

Dephosphorylation
Acetylation

Research Areas

Core ESC-Like Genes
mTOR Pathway
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF4B

References

PMID: 2390971 by Milburn S.C., et al. Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif.

PMID: 8139536 by Methot N., et al. The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence.