EIF4A2 Antibodies

AND EIF4A2 ELISA kits, EIF4A2 Proteins

Many biological assays use antibodies to detect EIF4A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF4A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF4A2 antibodies...

We validate the specificity of these antibodies to EIF4A2 by testing them on tissues known to express EIF4A2 positively and negatively. Browse below to find the EIF4A2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF4A2 Infographic by Boster Bio

All EIF4A2 Products

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Product

Figures

Specificity

Applications

Price

Anti-eIF4A2 Antibody Picoband®

4 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, IHC-F, ICC, WB

$370
Cat # PB9758
100 μg/vial

Anti-EIF4A2 Antibody

Human, Mouse, Rat

$405
Cat # A06549
100ul

EIF4A2 (NM_001967) Human Over-expression Lysate

Human

$628
Cat # LS001974
100 µg

EIF4A2 Overview

Facts about Eukaryotic initiation factor 4A-II.

EIF4A2 3D structure. Source: alphafold

Eukaryotic initiation factor 4A-II (EIF4A2)

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Gene Information

Human
Gene Name:	EIF4A2
Uniprot:	Q14240
Entrez:	1974

Family

Belongs to:

DEAD box helicase family

Alternative Names

ATP-dependent RNA helicase eIF4A-2; BM-010; DDX2Beukaryotic translation initiation factor 4A, isoform 2; EC 3.6.1; EC 3.6.4.13; EIF4A; eIF-4A-II; eIF4A-II; EIF4F; eukaryotic initiation factor 4A-II; eukaryotic translation initiation factor 4A; eukaryotic translation initiation factor 4A2

Molecular Weight

Mass (kDA):
46.402 kDA

Genomic Context


Human

Location:	3q27.3
Sequence:	3; NC_000003.12 (186783577..186789897)

Diseases

Malignant Neoplasms
Neoplasms
Malignant Paraganglionic Neoplasm
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Liver Diseases
Diabetic Nephropathy
Mood Disorders
Ectopic Pregnancy
Malignant Neoplasm Of Breast
Pleural Neoplasms
Malignant Pleural Mesothelioma

Carcinogenesis
Nonalcoholic Steatohepatitis
Nonalcoholic Fatty Liver Disease
Pleural Mesothelioma
Peritoneal Adhesion
Lymphoma
Rheumatoid Arthritis

Interacting Proteins

DPPA4
HSPB1
IPO11
MDFI
PDCD4

PIH1D2
SLC16A9
SSX2IP
TRIM36
TRIM39

Pathways

Translation
Cell Proliferation
Localization
Response To Stress
Jak-stat Cascade
Neurogenesis
Synaptic Transmission
Regulation Of Gene Expression
Hepatocyte Proliferation
Protein Metabolic Process

Glucose Homeostasis
Ribosome Biogenesis
Metabolic Process
Cell Growth
Regulation Of Translation

PTMs

Phosphoprotein

Research Areas

Cancer
mTOR Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF4A2

References

PMID: 8521730 by Sudo K., et al. Isolation and mapping of the human EIF4A2 gene homologous to the murine protein synthesis initiation factor 4A-II gene Eif4a2.

PMID: 11408474 by Li W., et al. Eukaryotic initiation factors 4A (eIF4A) and 4G (eIF4G) mutually interact in a 1:1 ratio in vivo.