EIF2B4 Antibodies

AND EIF2B4 ELISA kits, EIF2B4 Proteins

Many biological assays use antibodies to detect EIF2B4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF2B4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF2B4 antibodies...

We validate the specificity of these antibodies to EIF2B4 by testing them on tissues known to express EIF2B4 positively and negatively. Browse below to find the EIF2B4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF2B4 Infographic by Boster Bio

All EIF2B4 Products

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Specificity

Applications

Price

Anti-eIF2 delta EIF2B4 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A06320
100ul

EIF2B4 (NM_015636) Human Over-expression Lysate

Human

$960
Cat # LS008890
100 µg

EIF2B4 Overview

Facts about Translation initiation factor eIF-2B subunit delta.

EIF2B4 3D structure. Source: alphafold

Translation initiation factor eIF-2B subunit delta (EIF2B4)

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. .

Gene Information

Human
Gene Name:	EIF2B4
Uniprot:	Q9UI10
Entrez:	8890

Family

Belongs to:

eIF-2B alpha/beta/delta subunits family

Alternative Names

DKFZp586J0119; eIF-2B GDP-GTP exchange factor subunit delta; EIF2B; EIF-2B; EIF2BD; EIF2Bdelta; eukaryotic translation initiation factor 2B, subunit 4 (delta, 67kD); eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; translation initiation factor eIF-2b delta subunit; translation initiation factor eIF-2B subunit delta

Molecular Weight

Mass (kDA):
57.557 kDA

Genomic Context


Human

Location:	2p23.3
Sequence:	2; NC_000002.12 (27364352..27370457, complement)

Diseases

Leukoencephalopathies
Muscle Spasticity
Optic Atrophy
Ataxia
Atrophy
Leukoencephalopathy With Vanishing White Matter
Brain Diseases
Infective Disorder
Chronic Fatigue Syndrome
Craniocerebral Trauma

Nervous System Disorder
Cerebellar Ataxia
Virus Diseases
Neoplasms

Interacting Proteins

EIF2B2

Pathways

Translation
Cell Activation
Cell Death
T Cell Activation
Pathogenesis

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF2B4

References

PMID: 11835386 by van der Knaap M.S., et al. Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter.

PMID: 12707859 by Fogli A., et al. Ovarian failure related to eukaryotic initiation factor 2B mutations.