EHD2 Antibodies

EH domain-containing protein 2 (EHD2)

ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes (PubMed:17233914).

Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes.

Gene Information

Human
Gene Name:	EHD2
Uniprot:	Q9NZN4
Entrez:	30846

Family

Belongs to:
TRAFAC class dynamin-like GTPase superfamily

Alternative Names

EH domain containing 2; EH domain-containing protein 2; EH-domain containing 2; FLJ96617; PAST homolog 2; PAST2

Molecular Weight

Mass (kDA):
61.161 kDA

Genomic Context

Human
Location:	19q13.33
Sequence:	19; NC_000019.10 (47713422..47743134)

Tissue Specificity

Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, caveola; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes.

Diseases

• Neoplasms
• Glioma
• Cholera
• Malignant Neoplasms
• Stomach Neoplasms
• Muscle Injury
• Embryonal Carcinoma
• Infarction
• Malignant Paraganglionic Neoplasm
• Oligodendroglioma
• Mixed Oligodendroglioma-astrocytoma
• Tissue Adhesions
• Fibrolamellar Carcinoma

• Brain Neoplasms
• Carcinogenesis
• Carcinoma
• Cardiovascular Diseases
• Myocardial Infarction
• Malignant Neoplasm Of Stomach
• Foreign Body Of Body Structure

Pathways

• Endocytosis
• Endocytic Recycling
• Localization
• Transport
• Clathrin-mediated Endocytosis
• Defense Response
• Myoblast Fusion
• Cell Adhesion
• Hexose Transport
• Gene Silencing
• Protein Targeting
• Mitosis
• Dna Repair

• Regulation Of Gene Expression
• Membrane Fusion
• Nuclear Export
• Cell Cycle
• Membrane Assembly
• Receptor Recycling
• Fatty Acid Oxidation

PTMs

• Phosphorylation
• Sumoylation

• Oxidation
• Palmitoylation

• Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EHD2

Boster Bio - Best Uses Of The EHD2 Marker

Are you looking in high-affinity secondary antibodies to the EHD2Marker Boster Bio is a premier source for high-affinity primary antibodies. This company has developed highly-validated antibodies for over 25 years. Boster's antibodies have been validated for Western Blotting, Immunohistochemistry, and ELISA. Boster's Antibodies can produce high quality results.

Boster has high-affinity prima antibodies

It is important to choose the right antibody when you are searching for antibodies to study this marker's expression. The antibodies offered by Boster Bio are highly specific to this marker and have been validated for use in immunohistochemistry, Western Blotting, and ELISA. These antibodies offer a reliable and exact detection method. Additionally, they come with helpful troubleshooting instructions to help you make the most of them.

Using these primary antibodies in conjunction with secondary ones allows researchers to ask more questions of their specimens and provide more contextual data. Both antibodies can detect a single antigen so these tools will give you more information and a stronger answer. Boster Bio supplies high-affinity primary antibodies for the EHD2 marker. This will allow you to get the best results.

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