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, No Gclids
EGFR Antibodies
AND EGFR ELISA kits, EGFR Proteins
Many biological assays use antibodies to detect EGFR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EGFR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EGFR antibodies...
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EGFR Infographic by Boster Bio
All EGFR Products
Product
Figures
Specificity
Applications
Price
Mouse EGFR ELISA Kit PicoKine®
1 Citations 8 Q&As
Mouse
ELISA
$499
Cat # EK1433
96 wells/kit, with removable strips.
Cat # EK1433
96 wells/kit, with removable strips.
Human soluble EGFR ELISA Kit PicoKine®
8 Citations 8 Q&As
Human
ELISA
$499
Cat # EK0327
96 wells/kit, with removable strips.
Cat # EK0327
96 wells/kit, with removable strips.
Human
Flow Cytometry, IF
$486
Cat # M00023
100ug/vial
Cat # M00023
100ug/vial
Human, Mouse
IF, IHC, ICC, WB
$370
Cat # P00023
100 μl
Cat # P00023
100 μl
Human
IP, IF, ICC, WB
$370
Cat # P00023-1
100 μl
Cat # P00023-1
100 μl
Human
IP, IF, IHC, ICC, WB
$370
Cat # P00023-2
100 μl
Cat # P00023-2
100 μl
Human
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # P00023-3
100 μl
Cat # P00023-3
100 μl
Anti-EGFR (ErbB 1) Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00023-2
100 μl
Cat # M00023-2
100 μl
Human
IHC, WB
$431
Cat # P00023-5
100uL
Cat # P00023-5
100uL
Human, Mouse, Rat
ELISA
$480
Cat # EKC1185
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1185
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1939
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1939
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1940
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1940
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2065
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2065
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2251
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2251
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2388
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2388
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2389
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2389
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2390
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2390
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2391
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2391
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2392
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2392
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2393
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2393
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2545
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2545
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2546
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2546
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2547
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2547
1 kit, containing two 96-well plates and all necessary reagents
Human
Flow Cytometry, IP, IF, ICC, WB
$405
Cat # A00023Y1068-1
100ul
Cat # A00023Y1068-1
100ul
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00023Y1016
100ul
Cat # A00023Y1016
100ul
Anti-EGFR Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00023-4
100 μg/vial
Cat # A00023-4
100 μg/vial
Anti-EGFR Antibody Picoband®
2 Citations
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00023-5
100 μg/vial
Cat # A00023-5
100 μg/vial
Human
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M00023-4
100 μl/vial
Cat # M00023-4
100 μl/vial
Human
IF, IHC, ICC, WB
$370
Cat # M00023-5
100 μl/vial
Cat # M00023-5
100 μl/vial
Human
ELISA
$499
Cat # FEK0327
96 wells/kit, with removable strips.
Cat # FEK0327
96 wells/kit, with removable strips.
Human
IF, ICC, WB
$370
Cat # M00023Y845
100 µl/vial
Cat # M00023Y845
100 µl/vial
Mouse
ELISA
$499
Cat # FEK1433
96 wells/kit, with removable strips.
Cat # FEK1433
96 wells/kit, with removable strips.
Cynomolgus monkey, Human, Mouse
ELISA, Flow Cytometry, FTA
$349
Cat # M00023-6
100 μg
Cat # M00023-6
100 μg
EGFR Overview
Facts about Epidermal growth factor receptor.
Epidermal growth factor receptor (EGFR)
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Ligand binding activates receptor homo- and/or heterodimerization and autophosphorylation on crucial cytoplasmic residues.
The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules (PubMed:27153536).
Gene Information
| Human | |
|---|---|
| Gene Name: | EGFR |
| Uniprot: | P00533 |
| Entrez: | 1956 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10; EC 2.7.10.1; EGF R; EGFR; epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog); epidermal growth factor receptor; ErbB; ErbB1; ERBB1PIG61; HER1; HER-1; mENA; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Molecular Weight
Mass (kDA):
134.277 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7p11.2 |
| Sequence: | 7; NC_000007.14 (55019017..55211628) |
Tissue Specificity
Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome. Endosome membrane. Nucleus. In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546). Endocytosed upon activation by ligand (PubMed:2790960, PubMed:17182860, PubMed:27153536). Colocalized with GPER1 in the nucleus of estrogen agonist-induced cancer-associated fibroblasts (CAF) (PubMed:20551055).; [Iso
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Lung
- Lung Neoplasms
- Non-small Cell Lung Carcinoma
- Adenocarcinoma
- Malignant Neoplasm Of Breast
- Neoplasm Metastasis
- Malignant Squamous Cell Neoplasm
- Mammary Neoplasms
- Malignant Paraganglionic Neoplasm
Pathways
- Cell Proliferation
- Cell Growth
- Cell Cycle
- Angiogenesis
- Pathogenesis
- Localization
- Cell Death
- Cell Migration
- Endocytosis
- Secretion
- Drug Resistance
- Cell Adhesion
- Transport
PTMs
- Phosphorylation
- Cleavage
- Ubiquitination
- Methylation
- Dephosphorylation
- Glycosylation
- Acetylation
- Biotinylation
- Reduction
- Oxidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EGFR
bosterbio.com/bosterbio-gene-info-cards/EGFR
References
PMID: 6328312 by Ullrich A., et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells.
PMID: 7654368 by Ilekis J.V., et al. Possible role of variant RNA transcripts in the regulation of epidermal growth factor receptor expression in human placenta.
22 Publications of Boster EGFR Antibodies & ELISA Kits
- PubMed ID: 10.1186/s12935-021-02277-0, RHBDF2 gene functions are correlated to facilitated renal clear cell carcinoma p...
- PubMed ID: 10.1159/000101926, Epidermal Growth Factor Receptor in Cultured Human Retinal Pigment Epithelial Ce...
- PubMed ID: 10.1111/cbdd.12383, Synthesis and Evaluation of Salicylanilide Derivatives as Potential Epidermal Gr...
- PubMed ID: 10.1080/10286020.2019.1702028, Synthesis, characterization and preliminary biological evaluation of chrysin ami...
- PubMed ID: 10.1016/j.jff.2019.103523, Cultured Cordyceps sinensis polysaccharides attenuate cyclophosphamide-induced i...
- PubMed ID: 10.1016/j.jdiacomp.2018.11.007, Epidermal growth factor receptor and podocin predict nephropathy progression in ...
- PubMed ID: 10.1016/j.ejphar.2011.06.013, Inhibition of angiogenesis involves in anticancer activity of riccardin D, a mac...
- PubMed ID: 10.1016/j.bmcl.2020.127557, Design, synthesis and biological evaluation of novel heptamethine cyanine dye-er...
- PubMed ID: 33537094, Chen X,Gao A,Zhang F,Yang Z,Wang S,Fang Y,Li J,Wang J,Shi W,Wang L, Zheng Y,Sun ...
- PubMed ID: -, Study of the correlation between the expression of nuclear factor kappa B and pr...
- PubMed ID: 30545560 , Epidermal growth factor receptor and podocin predict nephropathy progression in ...
- PubMed ID: 29072695, Glucocorticoid mediates prenatal caffeine exposure-induced endochondral ossifica...
- PubMed ID: 27609096, Anti-tumor activity of erlotinib in the BxPC-3 pancreatic cancer cell line
- PubMed ID: 22507221, YC-1 exerts inhibitory effects on MDA-MB-468 breast cancer cells by targeting EG...
- PubMed ID: 2744159, Anti-tumor activity of erlotinib in the BxPC-3 pancreatic cancer cell line
- PubMed ID: 20092659, Gu Y, Zhang S, Wu Q, Xu S, Cui Y, Yang Z, Zhao X, Sun B. J Exp Clin Cancer Res. ...
- PubMed ID: 19263229, Wang Sb, Cheng Yn, Cui Sx, Zhong Jl, Ward Sg, Sun Lr, Chen Mh, Kokudo N, Tang W,...
- PubMed ID: 21349701, Yue P, Gao Zh, Xue X, Cui Sx, Zhao Cr, Yuan Y, Yin Z, Inagaki Y, Kokudo N, Tang ...
- PubMed ID: 21208277, Qin Li L, Huang Hl, Ping Jl, Xu W, Li J, Dai Lc. Apmis. 2011 Feb;119(2):103-10. ...
- PubMed ID: 24567178, Zhang H, Mao Y, Zhang F, Ye C, Tong H, Su Y, Zhu J. Mol Cell Biochem. 2014 Jun;3...
- PubMed ID: 22126621, Achmad A, Hanaoka H, Yoshioka H, Yamamoto S, Tominaga H, Araki T, Ohshima Y, Ori...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page