EDARADD Antibodies

AND EDARADD ELISA kits, EDARADD Proteins

Many biological assays use antibodies to detect EDARADD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EDARADD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EDARADD antibodies...

We validate the specificity of these antibodies to EDARADD by testing them on tissues known to express EDARADD positively and negatively. Browse below to find the EDARADD antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EDARADD Infographic by Boster Bio

All EDARADD Products

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Product

Figures

Specificity

Applications

Price

Anti-EDARADD Antibody

Human

$405
Cat # A06091
100ul

EDARADD (NM_145861) Human Over-expression Lysate

Human

$628
Cat # LS128178
100 µg

EDARADD Overview

Facts about Ectodysplasin-A receptor-associated adapter protein.

EDARADD 3D structure. Source: alphafold

Ectodysplasin-A receptor-associated adapter protein (EDARADD)

Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF- kappa-B.

Gene Information

Human
Gene Name:	EDARADD
Uniprot:	Q8WWZ3
Entrez:	128178

Family

Belongs to:

No superfamily

Alternative Names

crinkled homolog; ectodysplasia A receptor associated death domain; ectodysplasin A receptor associated adapter protein; ectodysplasin-A receptor-associated adapter protein; ED3; EDA3; EDAR-associated death domain protein; EDAR-associated death domain; Protein crinkled homolog

Molecular Weight

Mass (kDA):
24.802 kDA

Genomic Context


Human

Location:	1q42.3-q43
Sequence:	1; NC_000001.11 (236394286..236484930)

Tissue Specificity

Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis.

Subcellular Localizations

Cytoplasm.

Diseases

Dysplasia
Ectodermal Dysplasia
Christ-siemens-touraine Syndrome
Hypohidrosis
Hypodontia
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive
Hereditary Diseases
Anhydrotic Ectodermal Dysplasias
Developmental Absence Of Tooth
Congenital Abnormality
Tooth Loss
Congenital Absence
Immunologic Deficiency Syndromes

Congenital Disorders
Bloch Sulzberger Syndrome
Skin Diseases, Genetic
Hyperpigmentation
Respiration Disorders
De Novo Mutation
Congenital Anomaly Of Face

Interacting Proteins

RNF111
SDCBP
SHPRH
SUMO1
SUMO1P1

TRAF2
TRAF6
UBE2I
WDYHV1

Pathways

Gland Development
Appendage Development
Cell Adhesion
Hair Follicle Morphogenesis
Catagen
Regulation Of Signaling
Dna Methylation
Odontogenesis
Sweat Gland Development
Localization
Methylation
Hair Cycle

Anagen
Wound Healing
Organ Formation
Pathogenesis
Regulation Of Embryonic Development
Secretion

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDARADD

References

PMID: 11780064 by Headon D.J., et al. Gene defect in ectodermal dysplasia implicates a DEATH domain adapter in development.

PMID: 11882293 by Yan M., et al. Identification of a novel DEATH domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice.