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EDAR Antibodies
AND EDAR ELISA kits, EDAR Proteins
Many biological assays use antibodies to detect EDAR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EDAR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EDAR antibodies...
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EDAR Infographic by Boster Bio
All EDAR Products
Product
Figures
Specificity
Applications
Price
Human EDAR ELISA Kit PicoKine®
10 Q&As
Human
ELISA
$750
Cat # EK1851
96 wells/kit, with removable strips.
Cat # EK1851
96 wells/kit, with removable strips.
EDAR Overview
Facts about Tumor necrosis factor receptor superfamily member EDAR.
Tumor necrosis factor receptor superfamily member EDAR (EDAR)
Receptor for EDA isoform A1, but not for EDA isoform A2.
Mediates the activation of NF-kappa-B and JNK.May encourage caspase-independent cell death. .
Gene Information
| Human | |
|---|---|
| Gene Name: | EDAR |
| Uniprot: | Q9UNE0 |
| Entrez: | 10913 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Anhidrotic ectodysplasin receptor 1; DLED3; Ectodermal dysplasia receptor; ectodysplasin 1, anhidrotic receptor; ectodysplasin A receptor; Ectodysplasin-A receptor; ED1R; ED5; EDA1R; EDA3EDA-A1 receptor; EDA-A1R; EDAR; FLJ94390; HRM1; mouse, homolog of; tumor necrosis factor receptor superfamily member EDAR
Molecular Weight
Mass (kDA):
48.582 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q13 |
| Sequence: | 2; NC_000002.12 (108894471..108989256, complement) |
Tissue Specificity
Detected in fetal kidney, lung, skin and cultured neonatal epidermal keratinocytes. Not detected in lymphoblast and fibroblast cell lines.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Ectodermal Dysplasia
- Dysplasia
- Christ-siemens-touraine Syndrome
- Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive
- Hypodontia
- Hypohidrosis
- Anhydrotic Ectodermal Dysplasias
- Hereditary Diseases
- Developmental Absence Of Tooth
- Congenital Abnormality
- Tooth Loss
- Tooth Abnormalities
- Congenital Absence
Pathways
- Hair Follicle Development
- Gland Development
- Localization
- Cell Death
- Organ Development
- Hair Follicle Morphogenesis
- Appendage Development
- Cell Proliferation
- Cell Adhesion
- Sweat Gland Development
- Anagen
- Odontogenesis
- Regeneration
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDAR
bosterbio.com/bosterbio-gene-info-cards/EDAR
References
PMID: 10431241 by Monreal A.W., et al. Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia.
PMID: 11039935 by Yan M., et al. Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors.