EDA2R Antibodies

AND EDA2R ELISA kits, EDA2R Proteins

Many biological assays use antibodies to detect EDA2R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EDA2R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EDA2R antibodies...

We validate the specificity of these antibodies to EDA2R by testing them on tissues known to express EDA2R positively and negatively. Browse below to find the EDA2R antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EDA2R Infographic by Boster Bio

All EDA2R Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-XEDAR EDA2R Antibody

Human

ELISA, IHC-P, WB

$449
Cat # A08575
0.1 mg

Anti-TNR27 EDA2R Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08575-1
100ul

Human EDA2R/TNFRSF27/XEDAR Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9HAV5
Starting from 10ug

EDA2R (NM_021783) Human Over-expression Lysate

Human

$628
Cat # LS060401
100 µg

EDA2R Overview

Facts about Tumor necrosis factor receptor superfamily member 27.

EDA2R 3D structure. Source: alphafold

Tumor necrosis factor receptor superfamily member 27 (EDA2R)

Receptor for EDA isoform A2, but not for EDA isoform A1.
Mediates the activation of the NF-kappa-B and JNK pathways.

Activation seems to be mediated by binding to TRAF3 and TRAF6. .

Gene Information

Human
Gene Name:	EDA2R
Uniprot:	Q9HAV5
Entrez:	60401

Family

Belongs to:

No superfamily

Alternative Names

ectodysplasin A2 receptor; EDA2R; EDA-A2 receptor; EDAA2R; EDA-A2R; EDAA2Rtumor necrosis factor receptor superfamily member XEDAR; EDAR2; TNFRSF27; XEDAR; XEDARTNFRSF27tumor necrosis factor receptor superfamily member 27; X-linked ectodysplasin-A2 receptor

Molecular Weight

Mass (kDA):
32.759 kDA

Genomic Context


Human

Location:	Xq12
Sequence:	X; NC_000023.11 (66594384..66639303, complement)

Subcellular Localizations

Membrane; Single-pass type III membrane protein.

Diseases

Ectodermal Dysplasia
Dysplasia
Androgenetic Alopecia
Malignant Neoplasms
Dysequilibrium Syndrome
Carcinogenesis
Neoplasms
Colorectal Cancer
Christ-siemens-touraine Syndrome
Colorectal Neoplasms
Malignant Neoplasm Of Breast
Tumor Progression
Bone Neoplasms

De Novo Mutation
Malignant Neoplasm Of Lung
Osteosarcoma
Mammary Neoplasms
Ancell-spiegler Cylindromas
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm

Interacting Proteins

TRAF3
TRAF6

Pathways

Induction Of Apoptosis
Cell Death
Cell Adhesion
Hair Follicle Development
Cellular Homeostasis
Pigmentation
Localization
Methylation
Organ Development

Cell Differentiation
Anoikis
Cell Growth
Regulation Of Cell Differentiation

PTMs

Methylation

Demethylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDA2R

References

PMID: 11039935 by Yan M., et al. Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors.

PMID: 12270937 by Sinha S.K., et al. Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor.