EBP Antibodies

AND EBP ELISA kits, EBP Proteins

Many biological assays use antibodies to detect EBP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EBP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EBP antibodies...

We validate the specificity of these antibodies to EBP by testing them on tissues known to express EBP positively and negatively. Browse below to find the EBP antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EBP Infographic by Boster Bio

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emopamil binding protein (EBP) (NM_006579) Human Over-expression Lysate

Human

$628
Cat # LS010682
100 µg

EBP Overview

Facts about 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase.

EBP 3D structure. Source: alphafold

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP)

Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers.
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Gene Information

Human
Gene Name:	EBP
Uniprot:	Q15125
Entrez:	10682

Family

Belongs to:

EBP family

Alternative Names

3-beta-hydroxysteroid-Delta(8); CDPX2; Cholestenol Delta-isomerase; CPX3-beta-hydroxysteroid-delta-8; CPXDX-linked dominant (Happle syndrome); D8-D7 sterol isomerase; Delta(7)-isomerase; Delta(8)-Delta(7) sterol isomerase; delta-7-isomerase; EC 5.3.3.5; emopamil binding protein (sterol isomerase); Emopamil-binding protein; sterol 8-isomerase

Molecular Weight

Mass (kDA):
26.353 kDA

Genomic Context


Human

Location:	Xp11.23
Sequence:	X; NC_000023.11 (48521808..48528716)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope. Cytoplasmic vesicle. During interphase, detected on the endoplasmic reticulum and the nuclear envelope. During mitosis, detected on cytoplasmic vesicles.

Diseases

Inflammation
Malignant Neoplasms
Liver Carcinoma
Neoplasms
Headache
Carcinoma
Leukemia
Diabetes Mellitus
Obesity
Liver Neoplasms
Mammary Neoplasms
Chondrodysplasia Punctata

Tissue Adhesions
Endoplasmic Reticulum Stress
Intracranial Hypotension
Post-dural Puncture Headaches
Acute-phase Reaction
Hypotension Adverse Event
Mental Disorders

Interacting Proteins

C16orf58
CYB561

Pathways

Translation
Pathogenesis
Secretion
Localization
Cell Cycle
Cell Differentiation
Cell Growth
Cell Proliferation
Regeneration
Cell Death
Methylation
Transport
Inflammatory Response

Rna Interference
Acute-phase Response
Liver Regeneration
Long-term Memory
Immune Response
Regulation Of Gene Expression
Sensitization

PTMs

Phosphorylation
Acetylation
Methylation
Cleavage
Dephosphorylation
Demethylation
Sumoylation
Oxidation

Deacetylation
Ubiquitination
Glycosylation
Biotinylation
Reduction
Myristoylation
Hydroxylation
Deamination

Farnesylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EBP

References

PMID: 7706302 by Hanner M., et al. Phenylalkylamine Ca2+ antagonist binding protein. Molecular cloning, tissue distribution, and heterologous expression.

PMID: 8798407 by Silve S., et al. Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast.