GMEB1 Antibodies

AND GMEB1 ELISA kits, GMEB1 Proteins

Many biological assays use antibodies to detect GMEB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GMEB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GMEB1 antibodies...

We validate the specificity of these antibodies to GMEB1 by testing them on tissues known to express GMEB1 positively and negatively. Browse below to find the GMEB1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GMEB1 Infographic by Boster Bio

All GMEB1 Products

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Specificity

Applications

Price

GMEB1 (NM_024482) Human Recombinant Protein

$813
Cat # PROTQ9Y692
20 µg

GMEB1 (NM_024482) Human Over-expression Lysate

Human

$628
Cat # LS010691
100 µg

GMEB1 Overview

Facts about Glucocorticoid modulatory element-binding protein 1.

GMEB1 3D structure. Source: alphafold

Glucocorticoid modulatory element-binding protein 1 (GMEB1)

Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter.

Essential auxiliary element for the replication of parvoviruses. .

Gene Information

Human
Gene Name:	GMEB1
Uniprot:	Q9Y692
Entrez:	10691

Family

Belongs to:

No superfamily

Alternative Names

DNA-binding protein p96PIF; glucocorticoid modulatory element binding protein 1; glucocorticoid modulatory element-binding protein 1; GMEB-1; P96PIF; Parvovirus initiation factor p96; PIF p96; PIF96

Molecular Weight

Mass (kDA):
62.591 kDA

Genomic Context


Human

Location:	1p35.3
Sequence:	1; NC_000001.11 (28668782..28719353)

Subcellular Localizations

Nucleus. Cytoplasm. May be also cytoplasmic.

Diseases

Neuroblastoma
Hereditary Diseases
Premature Menopause
Ischemia
Nerve Degeneration
Hypoxia
Brain Hypoxia
Granulosa Cell Tumor
Edema
Blepharoptosis
Neoplasms

Nervousness
Blepharophimosis
Liver Neoplasms, Experimental
Anoxia
Brain Edema

Pathways

Dna Replication
Response To Oxidative Stress
Methylation
Induction Of Apoptosis
Cell Death
Single-stranded Dna Binding
Pathogenesis
Rna Interference

Receptor Transactivation
V(d)j Recombination

PTMs

Oxidation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GMEB1

References

PMID: 10386584 by Theriault J.R., et al. Cloning and characterization of hGMEB1, a novel glucocorticoid modulatory element binding protein.

PMID: 10523663 by Christensen J., et al. Two new members of the emerging KDWK family of combinatorial transcription modulators bind as a heterodimer to flexibly spaced PuCGPy half-sites.