Transcription factor E2F2 Antibodies

AND E2F2 ELISA kits, Transcription factor E2F2 Proteins

Many biological assays use antibodies to detect Transcription factor E2F2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor E2F2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor E2F2 antibodies...

We validate the specificity of these antibodies to Transcription factor E2F2 by testing them on tissues known to express E2F2 positively and negatively. Browse below to find the E2F2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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E2F2 Infographic by Boster Bio

All E2F2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Transcription factor E2F2 E2F2 Antibody Picoband®

1 Citations 4 Q&As

Human, Mouse, Rat

$370
Cat # PA1810
100 μg/vial

Anti-E2F2 Rabbit Monoclonal Antibody

1 Citations

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M02896
100 μl

Anti-E2F-2 (K236) Antibody

1 Citations

Human, Mouse, Rat

IHC

$405
Cat # A02896
100ul

E2F2 Overview

Facts about Transcription factor E2F2.

E2F2 3D structure. Source: alphafold

Transcription factor E2F2 (E2F2)

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a variety of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase.

E2F2 binds specifically to RB1 in a cell-cycle dependent manner. .

Gene Information

Human
Gene Name:	E2F2
Uniprot:	Q14209
Entrez:	1870

Family

Belongs to:

E2F/DP family

Alternative Names

E2F transcription factor 2; E2F2; E2F-2; E2F-2transcription factor E2F2

Molecular Weight

Mass (kDA):
47.506 kDA

Genomic Context


Human

Location:	1p36.12
Sequence:	1; NC_000001.11 (23505696..23531250, complement)

Tissue Specificity

Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasms
Retinoblastoma
Cell Transformation, Neoplastic
Hyperplasia
Carcinoma
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Breast
Mammary Neoplasms
Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Osteosarcoma
Autoimmunity

Hypertrophy
Tumor Progression
Glioma
Neoplasm Metastasis
Growth Arrest
Carcinogenesis
Leukemia

Interacting Proteins

Pathways

Cell Cycle
Cell Proliferation
S Phase
Cell Growth
Dna Replication
Cell Division
Cell Cycle Arrest
Cell Death
Oncogenesis
Senescence
Dna Repair
Regeneration
Mitosis

Localization
Cell Differentiation
Induction Of Apoptosis
Aging
Hepatocyte Proliferation
Liver Regeneration
Methylation

PTMs

Phosphorylation
Methylation
Acetylation

Cleavage
Reduction
Ubiquitination

Research Areas

Cell Cycle and Replication
Transcription Factors and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/E2F2

References

PMID: 8246995 by Ivey-Hoyle M., et al. Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F.

PMID: 16360038 by Rubin S.M., et al. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

1 Publications of Boster Transcription factor E2F2 Antibodies & ELISA Kits

PubMed ID: 26378521, GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling P...

*More publications can be found for each product on its corresponding product page