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- Table of Contents
Facts about Dual specificity protein phosphatase 13 isoform A.
Has a phosphatase activity- independent regulatory role in MAP3K5/ASK1-mediated apoptosis, preventing MAP3K5/ASK1 inhibition by AKT1. Shows no phosphatase activity on MAPK1/ERK2, MAPK8/JNK, MAPK14/p38 and MAP3K5/ASK1.
Mouse | |
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Gene Name: | Dusp13 |
Uniprot: | Q6B8I0 |
Entrez: | 27389 |
Belongs to: |
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protein-tyrosine phosphatase family |
Branching-enzyme interacting DSP; dual specificity phosphatase 13; Dual specificity phosphatase SKRP4; dual specificity protein phosphatase 13 isoform MDSP; dual specificity protein phosphatase 13; dual-specificity phosphatase SKRP4; DUSP13A; DUSP13B; EC 3.1.3.16; EC 3.1.3.48; FLJ32450; MDSPbranching-enzyme interacting dual-specificity protein phosphatase; Muscle-restricted DSP; Testis- and skeletal-muscle-specific DSP; TMDPBEDPSKRP4
Mass (kDA):
20.646 kDA
Mouse | |
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Location: | 14|14 A3 |
Sequence: | 14; |
Skeletal muscle-specific.
PMID: 15252030 by Chen H.-H., et al. Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2.