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DET1 homolog Antibodies

AND DET1 ELISA kits, DET1 homolog Proteins

Many biological assays use antibodies to detect DET1 homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DET1 homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DET1 homolog antibodies...

We validate the specificity of these antibodies to DET1 homolog by testing them on tissues known to express DET1 positively and negatively. Browse below to find the DET1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DET1 Infographic by Boster Bio

DET1 protein infographic

All DET1 Products

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Product

Figures

Specificity

Applications

Price

Anti-DET1 homolog DET1 Antibody

Human, Mouse, Rat

WB

$405
Cat # A10253
100ul

DET1 (NM_017996) Human Over-expression Lysate

Human

$960
Cat # LS055070
100 µg

DET1 Overview

Facts about DET1 homolog.

DET1 3D structure

DET1 3D structure. Source: alphafold

DET1 homolog (DET1)

Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is included in JUN ubiquitination and degradation.

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Gene Information

Human
Gene Name:	DET1
Uniprot:	Q7L5Y6
Entrez:	55070

Gene Information

Family

Belongs to:

DET1 family

Family

Alternative Names

de-etiolated 1; de-etiolated homolog 1 (Arabidopsis); De-etiolated-1 homolog; DET1 homolog; FLJ10103; MGC126156; MGC126157

Molecular Weight

Mass (kDA):
63.848 kDA

Molecular Weight

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (88501919..88546703, complement)

Tissue Specificity

Highly expressed in the ovary, some lymphoid organs and resting leukocytes.

Subcellular Localizations

Nucleus.

Subcellular Localization

Diseases

Feline Urological Syndrome
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Prostate
Adenocarcinoma
Cell Transformation, Neoplastic
Congenital Abnormality
Intraepithelial Neoplasia
Malignant Neoplasm Of Skin
Xeroderma
Genomic Instability
Hypoxia
Physiological Stress

Hypokinesia
Cancer Patients And Suicide And Depression
Prostatic Neoplasms
Headache
Dwarfism
Chromosomal Translocation
Hyperplasia

Disease

Pathways

Photomorphogenesis
Germination
Seedling Development
Seed Germination
De-etiolation
Transport
Gene Silencing
Proteolysis
Cell Cycle
Leaf Development
Localization
Rna Interference
Lateral Root Development

Dna Hypermethylation
Protein Targeting
Photosynthesis
Pigment Accumulation
Pigmentation
Regulation Of Gene Expression
Response To Blue Light

Pathways

PTMs

Ubiquitination
Phosphorylation
Cleavage

Acetylation
Methylation
Oxidation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DET1

References

PMID: 14739464 by Wertz I.E., et al. Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase.