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- Table of Contents
Facts about Differentially expressed in FDCP 8.
.
Mouse | |
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Gene Name: | Def8 |
Uniprot: | Q99J78 |
Entrez: | 23854 |
Belongs to: |
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DEF8 family |
DEF-8; differentially expressed in FDCP 8 homolog (mouse); differentially expressed in FDCP 8 homolog; FLJ20186; MGC104349
Mass (kDA):
52.311 kDA
Mouse | |
---|---|
Location: | 8 E1|8 72.1 cM |
Sequence: | 8; |
Abundantly expressed in peripheral blood leukocytes. Highly expressed in B-cells. Also present in lymph node and appendix. Down-regulated upon macrophage/granulocyte differentiation. Weakly expressed in bone marrow and spleen. Weakly or not expressed in thymus and fetal liver.
PMID: 10460589 by Hotfilder M., et al. Def-2, -3, -6 and -8, novel mouse genes differentially expressed in the haemopoietic system.
PMID: 27777970 by Fujiwara T., et al. PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.