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- Table of Contents
Facts about Serine/threonine-protein kinase DCLK1.
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Human | |
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Gene Name: | DCLK1 |
Uniprot: | O15075 |
Entrez: | 9201 |
Belongs to: |
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protein kinase superfamily |
CL1; CLICK1; DCAMKL1; DCAMKL1CLICK1; DCDC3A; DCDC3ACL1; DCLK; DCLK1; doublecortin and CaM kinase-like 1; Doublecortin domain-containing protein 3A; doublecortin-like kinase 1Doublecortin-like and CAM kinase-like 1; EC 2.7.11; KIAA0369EC 2.7.11.1; serine/threonine-protein kinase DCLK1
Mass (kDA):
82.224 kDA
Human | |
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Location: | 13q13.3 |
Sequence: | 13; NC_000013.11 (35768652..36131939, complement) |
In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain.
PMID: 9747029 by Omori Y., et al. Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin.
PMID: 10036192 by Sossey-Alaoui K., et al. DCAMKL1, a brain-specific transmembrane protein on 13q12.3 that is similar to doublecortin (DCX).