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DBT Antibodies
AND DBT ELISA kits, DBT Proteins
Many biological assays use antibodies to detect DBT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DBT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DBT antibodies...
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DBT Infographic by Boster Bio
All DBT Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, WB
$523
Cat # M01145
100 µl
Cat # M01145
100 µl
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, ICC, WB
$370
Cat # A01145-2
100 μg/vial
Cat # A01145-2
100 μg/vial
DBT Overview
Facts about Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial.
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (DBT)
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
Within this complex, the catalytic function of this enzyme is to take, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component. .
Gene Information
| Human | |
|---|---|
| Gene Name: | DBT |
| Uniprot: | P11182 |
| Entrez: | 1629 |
Family
| Belongs to: |
|---|
| 2-oxoacid dehydrogenase family |
Alternative Names
BCATE2BCKAD E2 subunit; BCKADE2; BCKAD-E2; branched chain acyltransferase, E2 component; Branched-chain alpha-keto acid dehydrogenase complex component E2; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto aciddehydrogenase complex; dihydrolipoamide branched chain transacylase (E2 component of branched chainketo acid dehydrogenase complex; maple syrup urine disease); dihydrolipoamide branched chain transacylase E2; Dihydrolipoamide branched chain transacylase; dihydrolipoyl transacylase; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; E2 component of branche
Molecular Weight
Mass (kDA):
53.487 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p21.2 |
| Sequence: | 1; NC_000001.11 (100186919..100249864, complement) |
Subcellular Localizations
Mitochondrion matrix.
Diseases
- Borderline Personality Disorder
- Personality Disorders
- Depressive Disorder
- Mammary Neoplasms
- Malignant Neoplasms
- Neoplasms
- Cancer Patients And Suicide And Depression
- Mental Disorders
- Anxiety Disorders
- Eating Disorders
- Hepatitis
Pathways
- Localization
- Dibenzothiophene Desulfurization
- Cell Proliferation
- Transport
- Circadian Rhythm
- Cell Growth
- Segmentation
- Hyperphosphorylation
- Phagocytosis
- Translation
- Regeneration
- Conjugation
- Swimming
PTMs
- Phosphorylation
- Oxidation
- Cleavage
- Reduction
- Methylation
- Nitration
Research Areas
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DBT
bosterbio.com/bosterbio-gene-info-cards/DBT
References
PMID: 1420314 by Lau K.S., et al. The complete cDNA sequence for dihydrolipoyl transacylase (E2) of human branched-chain alpha-keto acid dehydrogenase complex.
PMID: 3245861 by Hummel K.B., et al. Nucleotide sequence of a cDNA for branched chain acyltransferase with analysis of the deduced protein structure.