DZIP3 Antibodies

AND DZIP3 ELISA kits, DZIP3 Proteins

Many biological assays use antibodies to detect DZIP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DZIP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DZIP3 antibodies...

We validate the specificity of these antibodies to DZIP3 by testing them on tissues known to express DZIP3 positively and negatively. Browse below to find the DZIP3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DZIP3 Infographic by Boster Bio

All DZIP3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-DZIP3 Antibody

Human

ELISA, IHC, WB

$380
Cat # A11638
100ul

DZIP3 (NM_014648) Human Over-expression Lysate

Human

$628
Cat # LS009666
100 µg

DZIP3 Overview

Facts about E3 ubiquitin-protein ligase DZIP3.

DZIP3 3D structure. Source: alphafold

E3 ubiquitin-protein ligase DZIP3 (DZIP3)

E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases take ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Willing to specifically bind RNA. .

Gene Information

Human
Gene Name:	DZIP3
Uniprot:	Q86Y13
Entrez:	9666

Family

Belongs to:

No superfamily

Alternative Names

DAZ interacting protein 3, zinc finger; DAZ-interacting protein 3; E3 ubiquitin-protein ligase DZIP3; EC 6.3.2.-; FLJ13327; FLJ57977; FLJ58022; FLJ58223; hRUL138KIAA0675; human RNA-binding ubiquitin ligase of 138 kDa; RNA-binding ubiquitin ligase of 138 kDa; UURF2 ubiquitin ligase; UURF2; zinc finger DAZ interacting protein 3

Molecular Weight

Mass (kDA):
138.604 kDA

Genomic Context


Human

Location:	3q13.13
Sequence:	3; NC_000003.12 (108589490..108694840)

Tissue Specificity

Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.

Subcellular Localizations

Cytoplasm.

Diseases

Hepatitis
Hepatitis B

Interacting Proteins

AP1M1
ARHGAP32
CEP63
GTF2H2C
HNRNPF

HNRNPUL1
RBM4B
TOLLIP
ZCCHC10
ZNF24

ZNF765

Pathways

Histone H2a Monoubiquitination
Reverse Transcription

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DZIP3

References

PMID: 12538761 by Kreft S.G., et al. hRUL138, a novel human RNA-binding RING-H2 ubiquitin-protein ligase.

PMID: 12511597 by Moore F.L., et al. Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins.