SAFB2 Antibodies

AND SAFB2 ELISA kits, SAFB2 Proteins

Many biological assays use antibodies to detect SAFB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SAFB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SAFB2 antibodies...

We validate the specificity of these antibodies to SAFB2 by testing them on tissues known to express SAFB2 positively and negatively. Browse below to find the SAFB2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SAFB2 Infographic by Boster Bio

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Anti-Scaffold attachment factor B2 SAFB2 Antibody

Human, Mouse, Rat

$405
Cat # A06911
100ul

SAFB2 Overview

Facts about Scaffold attachment factor B2.

SAFB2 3D structure. Source: alphafold

Scaffold attachment factor B2 (SAFB2)

Binds to scaffold/matrix attachment region (S/MAR) DNA. Can be the estrogen receptor corepressor and may also inhibit cell proliferation.

Gene Information

Human
Gene Name:	SAFB2
Uniprot:	Q14151
Entrez:	9667

Family

Belongs to:

No superfamily

Alternative Names

KIAA0138SAF-B2; scaffold attachment factor B2

Molecular Weight

Mass (kDA):
107.473 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (5586993..5622846, complement)

Tissue Specificity

Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Cell Transformation, Neoplastic
Mutation, Out-of-frame
Malignant Neoplasm Of Ovary

Physiological Stress
Hereditary Breast Carcinoma

Interacting Proteins

ESR1
GABARAPL1
MAP1LC3B
SAFB

Pathways

Rna Splicing
Chromatin Organization
Cell Growth
Rna Processing
Protein Phosphorylation
Histone Deacetylation
Cell Cycle

Localization

PTMs

Phosphorylation

Deacetylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SAFB2

References

PMID: 12660241 by Townson S.M., et al. SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor.

PMID: 19674106 by Tsianou D., et al. The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2.