Dysferlin Antibodies

AND DYSF ELISA kits, Dysferlin Proteins

Many biological assays use antibodies to detect Dysferlin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dysferlin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dysferlin antibodies...

We validate the specificity of these antibodies to Dysferlin by testing them on tissues known to express DYSF positively and negatively. Browse below to find the DYSF antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: COLQ

DYSF Infographic by Boster Bio

All DYSF Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Dysferlin Antibody

4 Q&As

Human, Mouse

$360
Cat # A01234-1
100 µl

Anti-Dysferlin Rabbit Monoclonal Antibody

1 Q&As

Human, Mouse

IF, IHC, ICC, WB

$370
Cat # M01234
100 μl

Dysferlin Colorimetric Cell-Based ELISA Kit

Human, Mouse

ELISA

$480
Cat # EKC1177
1 kit, containing one 96-well plate and all necessary reagents

Anti-Dysferlin Antibody

Human, Mouse

IF, IHC, ICC, WB

$405
Cat # A01234-2
100ul

Anti-Dysferlin/DYSF Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01234-3
100 μg/vial

DYSF Overview

Facts about Dysferlin.

DYSF 3D structure. Source: alphafold

Dysferlin (DYSF)

Key calcium ion detector included in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity).

. .

Gene Information

Human
Gene Name:	DYSF
Uniprot:	O75923
Entrez:	8291

Family

Belongs to:

ferlin family

Alternative Names

dysferlin; dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive); dystrophy-associated fer-1-like 1; FER1L1Dystrophy-associated fer-1-like protein; Fer-1-like protein 1; FLJ00175; FLJ90168; LGMD2B

Molecular Weight

Mass (kDA):
237.295 kDA

Genomic Context


Human

Location:	2p13.2
Sequence:	2; NC_000002.12 (71453154..71686763)

Tissue Specificity

Expressed in skeletal muscle, myoblast, myotube and in the syncytiotrophoblast (STB) of the placenta (at protein level). Ubiquitous. Highly expressed in skeletal muscle. Also found in heart, brain, spleen, intestine, placenta and at lower levels in liver, lung, kidney and pancreas.

Subcellular Localizations

Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasmic vesicle membrane; Single-pass type II membrane protein. Cell membrane. Colocalizes, during muscle differentiation, with BIN1 in the T-tubule system of myotubules and at the site of contact between two myotubes or a myoblast and a myotube. Wounding of myotubes led to its focal enrichment to the site of injury and to its relocalization in a Ca(2+)-dependent manner toward the plasma membrane. Colocalizes with AHNAK, AHNAK2 and PARVB at the sarcolemma of skeletal muscle. Detected on the apical plasma membrane of the syncy