COLQ Antibodies

AND COLQ ELISA kits, COLQ Proteins

Many biological assays use antibodies to detect COLQ, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COLQ in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COLQ antibodies...

We validate the specificity of these antibodies to COLQ by testing them on tissues known to express COLQ positively and negatively. Browse below to find the COLQ antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COLQ Infographic by Boster Bio

All COLQ Products

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Product

Figures

Specificity

Applications

Price

Anti-COLQ Antibody

5 Q&As

Human, Mouse, Rat

IHC-P, WB, IF (paraffin)

$335
Cat # A03301
100ul

Anti-COLQ Antibody

Human, Mouse, Rat

IHC-P, WB

$380
Cat # A03301-1
100ul

COLQ (NM_005677) Human Over-expression Lysate

Human

$628
Cat # LS008292
100 µg

COLQ Overview

Facts about Acetylcholinesterase collagenic tail peptide.

COLQ 3D structure. Source: alphafold

Acetylcholinesterase collagenic tail peptide (COLQ)

Anchors the catalytic subunits of asymmetric AChE into the synaptic basal lamina. .

Gene Information

Human
Gene Name:	COLQ
Uniprot:	Q9Y215
Entrez:	8292

Family

Belongs to:

COLQ family

Alternative Names

acetylcholinesterase collagenic tail peptide; AChE Q subunit; collagenic tail of endplate acetylcholinesterase; collagen-like tail subunit (single strand of homotrimer) of asymmetricacetylcholinesterase; EADAcetylcholinesterase-associated collagen; FLJ55041; single strand of homotrimeric collagen-like tail subunit of asymmetricacetylcholinesterase

Molecular Weight

Mass (kDA):
47.766 kDA

Genomic Context


Human

Location:	3p25.1
Sequence:	3; NC_000003.12 (15450133..15521706, complement)

Tissue Specificity

Found at the end plate of skeletal muscle.

Subcellular Localizations

Cell junction, synapse.

Diseases

Myasthenic Syndromes, Congenital
Acetylcholinesterase Deficiency
Weakness
Nervousness
Myasthenias
Blepharoptosis
Myasthenia Gravis
Muscle Weakness
Ophthalmoplegia
Apnea
Mycoplasma Pneumonia
Autoimmune Reaction

Asthenia
Neuromuscular Diseases
Myopathy
Nails, Ingrown
Course Of Illness
Congenital Ptosis
Pertussis

Interacting Proteins

ACHE

Pathways

Localization
Synaptic Transmission
Regeneration
Secretory Pathway
Muscle Contraction
Innervation

Secretion

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COLQ

References

PMID: 9758617 by Donger C., et al. Mutation in the human acetylcholinesterase-associated collagen gene, COLQ, is responsible for congenital myasthenic syndrome with end-plate acetylcholinesterase deficiency (Type Ic).

PMID: 9689136 by Ohno K., et al. Human endplate acetylcholinesterase deficiency caused by mutations in the collagen-like tail subunit (ColQ) of the asymmetric enzyme.