DYNLT3 Antibodies

AND DYNLT3 ELISA kits, DYNLT3 Proteins

Many biological assays use antibodies to detect DYNLT3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DYNLT3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DYNLT3 antibodies...

We validate the specificity of these antibodies to DYNLT3 by testing them on tissues known to express DYNLT3 positively and negatively. Browse below to find the DYNLT3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DYNLT3 Infographic by Boster Bio

All DYNLT3 Products

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Product

Figures

Specificity

Applications

Price

Anti-DYLT3 DYNLT3 Antibody

Human

ELISA, WB

$380
Cat # A12158
100ul

Human DYNLT3 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP51808
Starting from 10ug

DYNLT3 (NM_006520) Human Over-expression Lysate

Human

$628
Cat # LS006990
100 µg

DYNLT3 Overview

Facts about Dynein light chain Tctex-type 3.

DYNLT3 3D structure. Source: alphafold

Dynein light chain Tctex-type 3 (DYNLT3)

Acts as one of many non-catalytic attachment components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins which regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.

Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity).

Gene Information

Human
Gene Name:	DYNLT3
Uniprot:	P51808
Entrez:	6990

Family

Belongs to:

dynein light chain Tctex-type family

Alternative Names

dynein, light chain, Tctex-type 3; Protein 91/23; RP3; T-complex-associated testis-expressed 1-like; t-complex-associated-testis-expressed 1-like; TCTE1Ldynein light chain Tctex-type 3; TCTE1XL; TCTEX1L

Molecular Weight

Mass (kDA):
13.062 kDA

Genomic Context


Human

Location:	Xp11.4
Sequence:	X; NC_000023.11 (37838836..37847571, complement)

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore. Colocalizes with BUB3 at kinetochores specifically during prometaphase.

Diseases

Malignant Neoplasms
Salivary Gland Neoplasms
Granulomatous Disorder
Granulomatous Disease, Chronic
Nerve Degeneration
Narcolepsy
Human Papilloma Virus Infection
Sleep Disorders
Parkinson Disease
Carcinoma
Misalignment
Adenoid Cystic Carcinoma

Papillomavirus Infections
Dental Plaque
Secondary Parkinson Disease
Traditional Serrated Adenoma
Sequence Inversion
Salivary Gland Adenoid Cystic Carcinoma

Interacting Proteins

DYNLT1
NIF3L1

Pathways

Transport
Localization
Intracellular Transport
Cell Proliferation
Mitosis
Metaphase
Chromosome Segregation
Demethylation
Methylation
Spindle Checkpoint

Cytoplasmic Transport
Homologous Chromosome Segregation
Meiosis I
Meiosis

PTMs

Demethylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DYNLT3

References

PMID: 8004092 by Roux A.-F., et al. Identification of a gene from Xp21 with similarity to the tctex-1 gene of the murine t complex.

PMID: 16079286 by Yeh T.-Y., et al. Dynein light chain rp3 acts as a nuclear matrix-associated transcriptional modulator in a dynein-independent pathway.