DYNLL1 Antibodies

AND DYNLL1 ELISA kits, DYNLL1 Proteins

Many biological assays use antibodies to detect DYNLL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DYNLL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DYNLL1 antibodies...

We validate the specificity of these antibodies to DYNLL1 by testing them on tissues known to express DYNLL1 positively and negatively. Browse below to find the DYNLL1 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DYNLL1 Infographic by Boster Bio

All DYNLL1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-DYNLL1/Pin Rabbit Monoclonal Antibody

5 Q&As

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M03454
100 μl

Anti-DYNLL1 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A03454
100ul

Anti-DYNLL1 Antibody

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$405
Cat # A03454-1
100ul

Anti-DYNLL1/PIN Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03454-2
100 μg/vial

DYNLL1 (NM_001037495) Human Recombinant Protein

$813
Cat # PROTP63167
20 µg

Anti-DYNLL1/PIN Antibody Picoband® (monoclonal, 6G2H1)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03454-1
100 μg/vial

DYNLL1 (NM_001037494) Human Over-expression Lysate

Human

$628
Cat # LS008655
100 µg

DYNLL1 Overview

Facts about Dynein light chain 1, cytoplasmic.

DYNLL1 3D structure. Source: alphafold

Dynein light chain 1, cytoplasmic (DYNLL1)

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.

May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. .

Gene Information

Human
Gene Name:	DYNLL1
Uniprot:	P63167
Entrez:	8655

Family

Belongs to:

dynein light chain family

Alternative Names

cytoplasmic dynein light polypeptide; DLC1; DLC1DNCLC1; DLC8; DLC8MGC126137; DNCL1; DNCL1MGC126138; DNCLC1; dynein light chain 1, cytoplasmic; Dynein light chain LC8-type 1; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1,8 kDa dynein light chain; DYNLL1; hdlc1; LC8; LC8a; PIN; PINLC8a; Protein inhibitor of neuronal nitric oxide synthase

Molecular Weight

Mass (kDA):
10.366 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (120469842..120498493)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Nucleus. Mitochondrion. Upon induction of apoptosis translocates together with BCL2L11 to mitochondria.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Virus Diseases
Classical Swine Fever
Neoplasms
Nervousness
Infective Disorder
African Swine Fever
Malignant Paraganglionic Neoplasm
Hypertensive Disease
Autoimmunity
Stenosis
Kartagener Syndrome

Ataxia
Cardiac Hypertrophy
Stomatitis
Fetal Alcohol Syndrome
Immunologic Deficiency Syndromes
Fibrosis
Dyskinetic Syndrome

Interacting Proteins

CCDC36
DNAL4
FAM117B
GPHN
IQUB

KANK2
MYZAP
NEK9
RACK1
SMCP

Pathways

Transport
Localization
Mitosis
Protein Folding
Pathogenesis
Anaphase
Cell Division
Cell Cycle
Nuclear Import
Cell Death
Autophagy
Mammary Gland Involution
Programmed Cell Death

Neurogenesis
Chromosome Segregation
V(d)j Recombination
Mitochondrial Transport
Reverse Transcription
Cell Motility
Sister Chromatid Cohesion

PTMs

Phosphorylation
Nitration

Reduction
Glycosylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DYNLL1

References

PMID: 8628263 by Dick T., et al. Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster.

PMID: 10198631 by Puthalakath H., et al. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex.