DYNC2LI1 Antibodies

AND DYNC2LI1 ELISA kits, DYNC2LI1 Proteins

Many biological assays use antibodies to detect DYNC2LI1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DYNC2LI1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DYNC2LI1 antibodies...

We validate the specificity of these antibodies to DYNC2LI1 by testing them on tissues known to express DYNC2LI1 positively and negatively. Browse below to find the DYNC2LI1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DYNC2LI1 Infographic by Boster Bio

All DYNC2LI1 Products

Product

Figures

Specificity

Applications

Price

Anti-DYNC2LI1 Antibody

Human, Mouse, Rat

$405
Cat # A12187
100ul

DC2L1 (DYNC2LI1) (NM_015522) Human Over-expression Lysate

Human

$628
Cat # LS051626
100 µg

DYNC2LI1 Overview

Facts about Cytoplasmic dynein 2 light intermediate chain 1.

DYNC2LI1 3D structure. Source: alphafold

Cytoplasmic dynein 2 light intermediate chain 1 (DYNC2LI1)

Required for proper intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length.

Gene Information

Human
Gene Name:	DYNC2LI1
Uniprot:	Q8TCX1
Entrez:	51626

Family

Belongs to:

dynein light intermediate chain family

Alternative Names

CGI-60; cytoplasmic dynein 2 light intermediate chain 1; D2LICDKFZp564A033; DKFZP564A033; dynein, cytoplasmic 2, light intermediate chain 1; LIC3Dynein 2 light intermediate chain

Molecular Weight

Mass (kDA):
39.625 kDA

Genomic Context


Human

Location:	2p21
Sequence:	2; NC_000002.12 (43774039..43828320)

Tissue Specificity

Expressed in bone, brain, kidney, and cartilage (PubMed:26077881, PubMed:26130459). Lower expression in heart, liver, lung, placenta and thymus (PubMed:26077881).

Subcellular Localizations

Cytoplasm. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes to the apical cytoplasm.

Diseases

Short-rib thoracic dysplasia 15 with polydactyly (SRTD15)

Interacting Proteins

SOD1

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DYNC2LI1

References

PMID: 11907264 by Grissom P.M., et al. Identification of a novel light intermediate chain (D2LIC) for mammalian cytoplasmic dynein 2.

PMID: 26077881 by Taylor S.P., et al. Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome.