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DYNC1LI1 Antibodies
AND DYNC1LI1 ELISA kits, DYNC1LI1 Proteins
Many biological assays use antibodies to detect DYNC1LI1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DYNC1LI1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DYNC1LI1 antibodies...
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DYNC1LI1 Infographic by Boster Bio
All DYNC1LI1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, WB
$523
Cat # M07529
100 µl
Cat # M07529
100 µl
Human
$960
Cat # LS051143
100 µg
Cat # LS051143
100 µg
DYNC1LI1 Overview
Facts about Cytoplasmic dynein 1 light intermediate chain 1.
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1)
Acts as one of several non-catalytic attachment components of the cytoplasmic dynein 1 complex that are thought to be involved in connecting dynein to cargos and to adapter proteins which regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin.
Gene Information
| Human | |
|---|---|
| Gene Name: | DYNC1LI1 |
| Uniprot: | Q9Y6G9 |
| Entrez: | 51143 |
Family
| Belongs to: |
|---|
| dynein light intermediate chain family |
Alternative Names
cytoplasmic dynein 1 light intermediate chain 1; DNCLI1; dynein, cytoplasmic 1, light intermediate chain 1; LIC1
Molecular Weight
Mass (kDA):
56.579 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p22.3 |
| Sequence: | 3; NC_000003.12 (32525971..32570924, complement) |
Subcellular Localizations
Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
Diseases
- Neoplasms
- Cytogenetic Abnormality
- Limb Deformities, Congenital
- Anxiety Disorders
- Liver Carcinoma
- Glioblastoma
- Glioma
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Liver
Interacting Proteins
- REL
Pathways
- Transport
- Intracellular Transport
- Cell Migration
- Metaphase
- Cytokinesis
- Mitosis
- Macropinocytosis
- Abscission
- Microtubule-based Transport
- Localization
- Anaphase
- Cell Division
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DYNC1LI1
bosterbio.com/bosterbio-gene-info-cards/DYNC1LI1
References
PMID: 19229290 by Sivaram M.V., et al. Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.
PMID: 20006841 by Bremner K.H., et al. Adenovirus transport via direct interaction of cytoplasmic dynein with the viral capsid hexon subunit.