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- Table of Contents
Facts about Cytoplasmic dynein 1 intermediate chain 1.
The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Human | |
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Gene Name: | DYNC1I1 |
Uniprot: | O14576 |
Entrez: | 1780 |
Belongs to: |
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dynein intermediate chain family |
cytoplasmic dynein 1 intermediate chain 1; Cytoplasmic dynein intermediate chain 1; DNCI1cytoplasmic, intermediate polypeptide 1; DNCIC1DH IC-1; Dynein intermediate chain 1, cytosolic; dynein, cytoplasmic 1, intermediate chain 1
Mass (kDA):
72.955 kDA
Human | |
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Location: | 7q21.3 |
Sequence: | 7; NC_000007.14 (95772506..96110322) |
Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
PMID: 10049579 by Crackower M.A., et al. Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human.
PMID: 19229290 by Sivaram M.V., et al. Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.