Double homeobox protein 4 Antibodies

AND DUX4 ELISA kits, Double homeobox protein 4 Proteins

Many biological assays use antibodies to detect Double homeobox protein 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Double homeobox protein 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Double homeobox protein 4 antibodies...

We validate the specificity of these antibodies to Double homeobox protein 4 by testing them on tissues known to express DUX4 positively and negatively. Browse below to find the DUX4 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DUX4 Infographic by Boster Bio

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DUX4 Overview

Facts about Double homeobox protein 4.

DUX4 3D structure. Source: alphafold

Double homeobox protein 4 (DUX4)

Involved in transcriptional regulation. May govern microRNA (miRNA) expression.

Gene Information

Human
Gene Name:	DUX4
Uniprot:	Q9UBX2
Entrez:	100288687

Family

Belongs to:

paired homeobox family

Alternative Names

double homeobox 4; double homeobox protein 10; double homeobox protein 4; double homeobox protein 4/10; double homeobox protein DUX10; DUX10; DUX4; DUX4L1

Molecular Weight

Mass (kDA):
44.94 kDA

Genomic Context


Human

Location:	4q35.2
Sequence:	4; NC_000004.12 (190173774..190185911)

Tissue Specificity

Does not seem to be expressed in normal muscle, but is detected in muscle of individuals with FSHD, and also in testis (at protein level) (PubMed:21060811). Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells.

Subcellular Localizations

[Isoform 1]: Nucleus. Actively transported through the nuclear pore complex (NPC).; [Isoform 2]: Nucleus.

Diseases

Facioscapulohumeral muscular dystrophy 1 (FSHD1)

Interacting Proteins

DES
Des
IPO13

Research Areas

Neuroscience
Transcription Factors and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DUX4

References

PMID: 10433963 by Gabrieels J., et al. Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.

PMID: 21060811 by Snider L., et al. Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene.