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DSPP Antibodies

AND DSPP ELISA kits, DSPP Proteins

Many biological assays use antibodies to detect DSPP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DSPP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DSPP antibodies...

We validate the specificity of these antibodies to DSPP by testing them on tissues known to express DSPP positively and negatively. Browse below to find the DSPP antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DSPP Infographic by Boster Bio

DSPP protein infographic

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Anti-Dentin sialophosphoprotein DSPP Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A01740
100ul

DSPP Overview

Facts about Dentin sialophosphoprotein.

DSPP 3D structure

DSPP 3D structure. Source: alphafold

Dentin sialophosphoprotein (DSPP)

DSP may be a significant factor in dentinogenesis. DPP may bind high quantity of calcium and facilitate initial mineralization of dentin matrix hydration as well as regulate the size and shape of the crystals.

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Gene Information

Human
Gene Name:	DSPP
Uniprot:	Q9NZW4
Entrez:	1834

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

dentin phosphoprotein; dentin sialophosphoprotein; dentin sialoprotein; DFNA39; DMP3; DTDP2

Molecular Weight

Mass (kDA):
131.151 kDA

Molecular Weight

Genomic Context


Human

Location:	4q22.1
Sequence:	4; NC_000004.12 (87608529..87616873)

Tissue Specificity

Expressed in teeth. DPP is synthesized by odontoblast and transiently expressed by pre-ameloblasts.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Subcellular Localization

Diseases

Dentinogenesis Imperfecta
Dysplasia
Dentin Dysplasia
Neoplasms
Malignant Neoplasms
Dentin, Secondary
Tissue Adhesions
Carcinoma
Dental Pulp Calcification
Amelogenesis Imperfecta
Congenital Absence
Impacted Tooth
Crest Syndrome

Mutation, Out-of-frame
Pulp Stones
Tooth Abnormalities
Malignant Squamous Cell Neoplasm
Osteogenesis Imperfecta
Mouth Neoplasms
Rickets

Disease

Pathways

Dentinogenesis
Odontoblast Differentiation
Regeneration
Dentin Mineralization
Cell Differentiation
Odontogenesis
Cell Proliferation
Amelogenesis
Secretion
Localization
Pathogenesis
Cell Cycle
Cell Growth

Cell Adhesion
Osteoblast Differentiation
Translation
Ossification
Bone Mineralization
Glycosylation
Root Development

Pathways

PTMs

Cleavage
Phosphorylation
Glycosylation

Reduction
Phosphorothioation
Methylation

Dephosphorylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DSPP

References

PMID: 10706475 by Gu K., et al. Molecular cloning of a human dentin sialophosphoprotein gene.

PMID: 9879917 by Gu K., et al. Human dentin phosphophoryn nucleotide and amino acid sequence.