Desmoplakin Antibodies

AND DSP ELISA kits, Desmoplakin Proteins

Many biological assays use antibodies to detect Desmoplakin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Desmoplakin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Desmoplakin antibodies...

We validate the specificity of these antibodies to Desmoplakin by testing them on tissues known to express DSP positively and negatively. Browse below to find the DSP antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DSP Infographic by Boster Bio

All DSP Products

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Specificity

Applications

Price

Anti-Desmoplakin/DSP Antibody Picoband®

17 Q&As

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A00616-1
100 μg/vial

Anti-Desmoplakin DSP Antibody

Human, Mouse

$405
Cat # A00616
100ul

Anti-Desmoplakin Rabbit Monoclonal Antibody

Human, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M00616
100 μl/vial

Anti-Desmoplakin/DSP Antibody Picoband®

1 Citations

Human

ELISA, Flow Cytometry, WB

$370
Cat # A00616-2
100 μg/vial

DSP Overview

Facts about Desmoplakin.

Desmoplakin (DSP)

Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin- plakoglobin complexes to discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

Gene Information

Human
Gene Name:	DSP
Uniprot:	P15924
Entrez:	1832

Family

Belongs to:

plakin or cytolinker family

Alternative Names

250/210 kDa paraneoplastic pemphigus antigen; DCWHKTA; desmoplakin (DPI, DPII); desmoplakin I; desmoplakin II; Desmoplakin; DP; DPI; DPII; DSP; KPPS2; PPKS2

Molecular Weight

Mass (kDA):
331.774 kDA

Genomic Context


Human

Location:	6p24.3
Sequence:	6; NC_000006.12 (7541671..7586714)

Tissue Specificity

Isoform DPI is apparently an obligate constituent of all desmosomes. Isoform DPII resides predominantly in tissues and cells of stratified origin.

Subcellular Localizations

Cell junction, desmosome. Cytoplasm, cytoskeleton. Cell membrane. Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network (PubMed:12802069). Localizes at the intercalated disk in cardiomyocytes (By similarity).