Desmocollin-3 Antibodies

AND DSC3 ELISA kits, Desmocollin-3 Proteins

Many biological assays use antibodies to detect Desmocollin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Desmocollin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Desmocollin-3 antibodies...

We validate the specificity of these antibodies to Desmocollin-3 by testing them on tissues known to express DSC3 positively and negatively. Browse below to find the DSC3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DSC3 Infographic by Boster Bio

All DSC3 Products

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Specificity

Applications

Price

Anti-Desmocollin-3 DSC3 Antibody

Human

ELISA, WB

$380
Cat # A05095
100ul

Anti-Desmocollin-3 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M05095
100 μl/vial

DSC3 Overview

Facts about Desmocollin-3.

DSC3 3D structure. Source: alphafold

Desmocollin-3 (DSC3)

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. .

Gene Information

Human
Gene Name:	DSC3
Uniprot:	Q14574
Entrez:	1825

Family

Belongs to:

No superfamily

Alternative Names

Cadherin family member 3; CDHF3; CDHF3HT-CP; desmocollin 3; Desmocollin3; Desmocollin-3; desmocollin-4; DSC; DSC1; DSC2; DSC3; DSC4; DSC4desmocollin-3; HT-CP

Molecular Weight

Mass (kDA):
99.969 kDA

Genomic Context


Human

Location:	18q12.1
Sequence:	18; NC_000018.10 (30989365..31042815, complement)

Tissue Specificity

Epidermis, buccal mucosa, esophagus and cervix.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.

Diseases

Tissue Adhesions
Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Squamous Cell Neoplasm
Adenocarcinoma
Dental Plaque
Bulla
Dermatologic Disorders
Malignant Neoplasm Of Lung
Autoimmune Reaction

Carcinogenesis
Colorectal Cancer
Malignant Neoplasm Of Breast
Mammary Neoplasms
Colorectal Neoplasms
Lung Neoplasms

Pathways

Cell-cell Adhesion
Cell Adhesion
Methylation
Cell Proliferation
Dna Methylation
Demethylation
Dna Hypermethylation
Desmosome Assembly
Keratinocyte Differentiation
Epithelial Cell Proliferation
Localization
Pathogenesis
Keratinization

Epithelial Cell-cell Adhesion
Hair Follicle Development
Gene Silencing
Proteolysis
Skin Development
Histone Modification
Virulence

PTMs

Methylation
Demethylation

Phosphorylation
Cleavage

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DSC3

References

PMID: 7929347 by Kawamura K., et al. cDNA cloning and expression of a novel human desmocollin.

PMID: 7665906 by King I.A., et al. The desmocollins of human foreskin epidermis: identification and chromosomal assignment of a third gene and expression patterns of the three isoforms.