D(2) dopamine receptor Antibodies

D(2) dopamine receptor (DRD2)

Dopamine receptor whose action is mediated by G proteins that inhibit adenylyl cyclase. .

Gene Information

Human
Gene Name:	DRD2
Uniprot:	P14416
Entrez:	1813

Family

Belongs to:
G-protein coupled receptor 1 family

Alternative Names

D(2) dopamine receptor; D2DR; D2R; Dopamine D2 R; Dopamine D2 receptor; Dopamine D2R; dopamine receptor D2 isoform; dopamine receptor D2; DRD2; seven transmembrane helix receptor

Molecular Weight

Mass (kDA):
50.619 kDA

Genomic Context

Human
Location:	11q23.2
Sequence:	11; NC_000011.10 (113409595..113475398, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

• Schizophrenia
• Mental Disorders
• Dysequilibrium Syndrome
• Depressive Disorder
• Variable Number Tandem Repeat
• Attention Deficit Hyperactivity Disorder
• Parkinson Disease
• Obesity
• Bipolar Disorder
• Substance-related Disorders
• Psychotic Disorders
• Tobacco Use Disorder

• Mood Disorders
• Anxiety Disorders
• Dyskinetic Syndrome
• Nicotine Dependence
• Malnutrition
• Cholangiocarcinoma

Interacting Proteins

• ADORA2A
• Arrb1
• DRD4
• GNAI1
• NTSR1

• SIGMAR1
• SLC6A3

Pathways

• Pathogenesis
• Secretion
• Methylation
• Dna Methylation
• Cognition
• Localization
• Translation
• Sensitization
• Transport
• Aging
• Gene Silencing
• Response To Risperidone

• Drinking Behavior
• Prepulse Inhibition
• Prolactin Secretion
• Locomotion
• Hypersensitivity
• Social Behavior
• Innervation

PTMs

• Methylation
• Phosphorylation

• Acetylation
• Reduction

• Glycosylation

Research Areas

• GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DRD2

Best Uses Of The DRD2 Marker

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Boster Bio optimization guides are a solution to those questions.

A Boster Bio optimization guide is an excellent resource for anyone wanting to improve their flow cytometry research. This guide will cover everything you need to learn about sample preparation, optimization techniques, and troubleshooting. Each researcher will need to answer numerous questions during experiments. In these tutorials, you'll learn to avoid common mistakes and improve your results. Learn about the most frequently asked questions customers have. These guides will provide you with valuable information on how to accurately measure antibodies and use them to maximize signal.

Immunohistochemistry detects antigens in cells. It works on the basis that antibodies can bind to antigens. In any immunohistochemistry test, proper sample preparation is vital. An IHC optimization guide from Boster Bio covers sample preparation methods, including fixing, retrieval of antigens, embedding, and sample preparation. The guides also provide advice on how to preserve various kinds of tissues, which are essential for a good staining.

Boster Bio troubleshooting guides eliminate the possibility of errors arising from

Every researcher will encounter some type of error during their experiments. These errors can be eliminated by using proper controls. Troubleshooting guides for Boster Bio ELISAs can help you avoid the most common problems. Boster's technical blog gives tips and tricks for ELISA applications and provides explanations of how ELISA protocols work. Additionally, you will find information about how to use Boster products.

Steven Boster's history

After spending most of his working life in biotechnology, Steven Boster branched out and founded his own business, Molecular Diagnostics. It was the most well-known Chinese antibody catalog company in the 1990s thanks to its success. The first product he launched called a diagnostic kit was the first step in the company's story. He soon developed hundreds of primary antibodies. PicoKine(tm), an exclusive ELISA platform, was developed in the latter part of 1990. The platform's success enabled it to develop high sensitivity ELISA kits.