Dermatopontin Antibodies

AND DPT ELISA kits, Dermatopontin Proteins

Many biological assays use antibodies to detect Dermatopontin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dermatopontin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dermatopontin antibodies...

We validate the specificity of these antibodies to Dermatopontin by testing them on tissues known to express DPT positively and negatively. Browse below to find the DPT antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN2 Next: DPYS

DPT Infographic by Boster Bio

All DPT Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Dermatopontin/DPT Antibody Picoband®

3 Q&As

Human, Mouse, Rat

ELISA, WB

$370
Cat # A02642-1
100 μg/vial

Human Dermatopontin/DPT ELISA Kit PicoKine®

1 Citations 10 Q&As

Human

ELISA

$499
Cat # EK1633
96 wells/kit, with removable strips.

Dermatopontin (DPT) (NM_001937) Human Over-expression Lysate

Human

$628
Cat # LS001805
100 µg

DPT Overview

Facts about Dermatopontin.

DPT 3D structure. Source: alphafold

Dermatopontin (DPT)

Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment.

Enhances TGFB1 activity. Inhibits cell proliferation.

Gene Information

Human
Gene Name:	DPT
Uniprot:	Q07507
Entrez:	1805

Family

Belongs to:

dermatopontin family

Alternative Names

Dermatopontin; DPT; Eq1; TRAMP; Tyrosine-rich acidic matrix protein

Molecular Weight

Mass (kDA):
24.005 kDA

Genomic Context


Human

Location:	1q24.2
Sequence:	1; NC_000001.11 (168695468..168729206, complement)

Tissue Specificity

Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Tetanus
Diphtheria
Pertussis
Measles
Poliomyelitis
Whooping Cough Due To Unspecified Organism
Asthma
Influenza
Infective Disorder
Hepatitis
Hepatitis B
Neoplasms
Allergy

Pain
Rhinorrhea
Bacterial Infections
Coughing
Tuberculosis
Malnutrition
Malignant Neoplasms

Interacting Proteins

Pathways

Immune Response
Sensitization
Hypersensitivity
Transport
Pathogenesis
Localization
Secretion
Cell Proliferation
Innate Immune Response
Translation
Anaphylaxis
Aging
Virulence

Cell Cycle
Cytokine Production
Cell Death
Glycosylation
Humoral Immune Response
Inflammatory Response
Phagocytosis

PTMs

Cleavage
Glycosylation
Nitration
Phosphorylation
Methylation
Amidation

Myristoylation
Sulphation
Demethylation
Hydroxylation
Deamination
Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DPT

References

PMID: 8104875 by Superti-Furga A., et al. Complementary DNA sequence and chromosomal mapping of a human proteoglycan-binding cell-adhesion protein (dermatopontin).

PMID: 10233760 by Kuroda K., et al. Dermatopontin expression is decreased in hypertrophic scar and systemic sclerosis skin fibroblasts and is regulated by transforming growth factor-beta1, interleukin-4, and matrix collagen.

1 Publications of Boster Dermatopontin Antibodies & ELISA Kits

PubMed ID: 10.3892/ol.2018.9187, H19 contributes to poor clinical features in NSCLC patients and leads to enhance...

*More publications can be found for each product on its corresponding product page