DPH1 Antibodies

AND DPH1 ELISA kits, DPH1 Proteins

Many biological assays use antibodies to detect DPH1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DPH1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DPH1 antibodies...

We validate the specificity of these antibodies to DPH1 by testing them on tissues known to express DPH1 positively and negatively. Browse below to find the DPH1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DPH1 Infographic by Boster Bio

All DPH1 Products

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OVCA1 (DPH1) (NM_001383) Human Recombinant Protein

$813
Cat # PROTQ9BZG8
20 µg

OVCA1 (DPH1) (NM_001383) Human Over-expression Lysate

Human

$960
Cat # LS001801
100 µg

DPH1 Overview

Facts about 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1.

DPH1 3D structure. Source: alphafold

2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (DPH1)

Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which happens in translation elongation factor 2 (EEF2). When overexpressed, suppresses colony formation ability and increase rate of ovarian cancer cells.

Acts also as a tumor suppressor in breast and lung cancers (By similarity). Plays a role in embryonic growth, organogenesis and postnatal survival (By similarity).

Gene Information

Human
Gene Name:	DPH1
Uniprot:	Q9BZG8
Entrez:	1801

Family

Belongs to:

DPH1/DPH2 family

Alternative Names

Diphthamide biosynthesis protein 2 homolog-like 1; Diphthamide biosynthesis protein 2-like; diptheria toxin resistance protein required for diphthamide biosynthesis(Saccharomyces)-like 1; diptheria toxin resistance protein required for diphthamide biosynthesis-like 1; diptheria toxin resistance protein required for diphthamide biosynthesis-like 1(S. cerevisiae); DPH1 homolog (S. cerevisiae); DPH1 homolog; DPH2L; DPH2L1diphthamide biosynthesis protein 1; DPH2-like 1; DPH-like 1 (S. cerevisiae); DPH-like 1; FLJ33211; hsDph1; Ovarian cancer-associated gene 1 protein; ovarian tumor suppressor cand

Molecular Weight

Mass (kDA):
48.805 kDA

Genomic Context


Human

Location:	17p13.3
Sequence:	17; NC_000017.11 (2030112..2044967)

Tissue Specificity

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, mammary gland, colon, small intestine, testis and ovary. Reduced expression in primary breast and ovarian tumors.