Protein Dok-7 Antibodies

AND Dok7 ELISA kits, Protein Dok-7 Proteins

Many biological assays use antibodies to detect Protein Dok-7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Dok-7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Dok-7 antibodies...

We validate the specificity of these antibodies to Protein Dok-7 by testing them on tissues known to express Dok7 positively and negatively. Browse below to find the Dok7 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Dok7 Infographic by Boster Bio

All Dok7 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Protein Dok-7 DOK7 Antibody

Human, Mouse

IF, IHC, WB

$360
Cat # A05165
100 µl

Anti-DOK7 Antibody Picoband®

1 Citations 3 Q&As

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # A05165-1
100 μg/vial

DOK7 Colorimetric Cell-Based ELISA

Human, Mouse

ELISA

$480
Cat # EKC1841
1 kit, containing one 96-well plate and all necessary reagents

DOK7 (NM_173660) Human Recombinant Protein

$1249
Cat # PROTQ18PE1
20 µg

Anti-DOK7 Mouse Monoclonal Antibody [Clone ID: OTI1A9]

Human, Mouse

Flow Cytometry, IF, IHC, WB

$523
Cat # M05165
100 µl

DOK7 (NM_173660) Human Over-expression Lysate

Human

$628
Cat # LS285489
100 µg

Dok7 Overview

Facts about Protein Dok-7.

Protein Dok-7 (Dok7)

Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes.

Induces autophosphorylation of MUSK. .

Gene Information

Mouse
Gene Name:	Dok7
Uniprot:	Q18PE0
Entrez:	231134

Family

Belongs to:

No superfamily

Alternative Names

C4orf25; C4orf25chromosome 4 open reading frame 25; CMS1B; docking protein 7; DOK7; Dok-7; Downstream of tyrosine kinase 7; FLJ33718; FLJ39137; FLJ90556; protein Dok-7

Molecular Weight

Mass (kDA):
53.177 kDA

Genomic Context


Mouse

Location:	5\|5 B2
Sequence:	5;

Diseases

Myasthenic Syndromes, Congenital
Weakness
Myasthenias
Muscle Weakness
Myasthenia Gravis
Autoimmune Reaction
Autoimmune Diseases
Blepharoptosis
Muscular Dystrophies, Limb-girdle
Myopathy
Malignant Neoplasms

Neoplasms
Stridor
Mycoplasma Pneumonia
Pena-shokeir Syndrome Type I
Gait Disorders, Neurologic

Pathways

Localization
Pathogenesis
Muscle Contraction
Dna Hypermethylation
Aging
Dna Methylation
Synaptic Transmission
Muscle Atrophy
Nuclear Export
Methylation
Regeneration

System Development
Nervous System Development
Skeletal Muscle Contraction
Segmentation
Innervation
Nuclear Import

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dok7

References

PMID: 16794080 by Okada K., et al. The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.

PMID: 20603078 by Bergamin E., et al. The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization.

1 Publications of Boster Protein Dok-7 Antibodies & ELISA Kits

PubMed ID: 10.1016/j.biopha.2018.06.156, Repression of Dok7 expression mediated by DNMT1 promotes glioma cells proliferat...

*More publications can be found for each product on its corresponding product page