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DNER Antibodies
AND DNER ELISA kits, DNER Proteins
Many biological assays use antibodies to detect DNER, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNER in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNER antibodies...
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DNER Infographic by Boster Bio
All DNER Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$750
Cat # EK2080
96 wells/kit, with removable strips.
Cat # EK2080
96 wells/kit, with removable strips.
Mouse
ELISA
$750
Cat # EK2081
96 wells/kit, with removable strips.
Cat # EK2081
96 wells/kit, with removable strips.
DNER Overview
Facts about Delta and Notch-like epidermal growth factor-related receptor.
Delta and Notch-like epidermal growth factor-related receptor (DNER)
Activator of the NOTCH1 pathway.
May mediate neuron-glia interaction during astrocytogenesis (By similarity).. .
Gene Information
| Human | |
|---|---|
| Gene Name: | DNER |
| Uniprot: | Q8NFT8 |
| Entrez: | 92737 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
bet; delta and Notch-like epidermal growth factor-related receptor; delta/notch-like EGF repeat containing; delta-notch-like EGF repeat-containing transmembrane; DNER; H_NH0150O02.1; UNQ26; WUGSC:H_NH0150O02.1
Molecular Weight
Mass (kDA):
78.475 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q36.3 |
| Sequence: | 2; NC_000002.12 (229357629..229714555, complement) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Nervousness
- Ataxia
- Lymphoma
- Hodgkin Disease
- Mutation Abnormality
- Malnutrition
- Virus Shedding
- Malignant Neoplasm Of Brain
- Epilepsy, Generalized
Pathways
- Transport
- Cell Differentiation
- Cell Proliferation
- Localization
- Cell Cycle
- Endocytosis
- Notch Signaling Pathway
- Stem Cell Differentiation
- Proteolysis
- Inner Ear Development
- Keratinocyte Differentiation
- System Development
- Axon Guidance
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DNER
bosterbio.com/bosterbio-gene-info-cards/DNER
References
PMID: 11950833 by Eiraku M., et al. Delta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons.
PMID: 11997712 by Nishizumi H., et al. BET, a novel neuronal transmembrane protein with multiple EGF-like motifs.