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- Table of Contents
Facts about DnaJ homolog subfamily B member 1.
Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery period length of the heat shock response (PubMed:9499401). Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).
Human | |
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Gene Name: | DNAJB1 |
Uniprot: | P25685 |
Entrez: | 3337 |
Belongs to: |
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No superfamily |
DnaJ (Hsp40) homolog, subfamily B, member 1; DnaJ (Hsp40) homolog, subfmaily B, member 1; dnaJ homolog subfamily B member 1; DnaJ protein homolog 1; DNAJ1; DNAJB1; Hdj1; hDj-1; Heat shock 40 kDa protein 1; heat shock 40kD protein 1; Heat shock protein 40; HSP40; HSPF1; HSPF1Hdj1; Human DnaJ protein 1; radial spoke 16 homolog B; RSPH16B; Sis1
Mass (kDA):
38.044 kDA
Human | |
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Location: | 19p13.12 |
Sequence: | 19; NC_000019.10 (14514764..14530597, complement) |
Cytoplasm. Nucleus. Nucleus, nucleolus. Translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock.
PMID: 1754405 by Raabe T., et al. A human homologue of the Escherichia coli DnaJ heat-shock protein.
PMID: 8250930 by Ohtsuka K.; Cloning of a cDNA for heat-shock protein hsp40, a human homologue of bacterial DnaJ.