Delta-like protein 4 Antibodies

AND Dll4 ELISA kits, Delta-like protein 4 Proteins

Many biological assays use antibodies to detect Delta-like protein 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Delta-like protein 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Delta-like protein 4 antibodies...

We validate the specificity of these antibodies to Delta-like protein 4 by testing them on tissues known to express Dll4 positively and negatively. Browse below to find the Dll4 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Dll4 Infographic by Boster Bio

All Dll4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Rat DLL4 ELISA Kit PicoKine®

6 Q&As

Rat

ELISA

$499
Cat # EK1570
96 wells/kit, with removable strips.

Mouse DLL4 ELISA Kit PicoKine®

7 Q&As

Mouse

ELISA

$499
Cat # EK1277
96 wells/kit, with removable strips.

Anti-DELTA-4 DLL4 Antibody

4 Q&As

Human, Mouse

ELISA, IHC, WB

$158
Cat # A00875-2
25uL

Mouse DLL4 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9JI71
Starting from 10ug

Anti-DLL4 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00875-4
100 µg/vial

Dll4 Overview

Facts about Delta-like protein 4.

Delta-like protein 4 (Dll4)

Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4.

Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (By similarity). Essential for retinal progenitor proliferation.

Gene Information

Mouse
Gene Name:	Dll4
Uniprot:	Q9JI71
Entrez:	54485

Family

Belongs to:

No superfamily

Alternative Names

Delta 4 precursor; delta 4; delta ligand 4; delta4; delta-like 4 (Drosophila); delta-like 4 homolog (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4

Molecular Weight

Mass (kDA):
74.991 kDA

Genomic Context


Mouse

Location:	2\|2 E5
Sequence:	2;

Tissue Specificity

Expressed in vascular endothelium. Expressed in retina at least during embryogenesis.

Diseases

Tumor Angiogenesis
Neoplasms
Pathologic Neovascularization
Malignant Neoplasms
Hypoxia
Carcinoma
Leukemia
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Mammary Neoplasms
Malignant Paraganglionic Neoplasm
Cell Invasion

Inflammation
Tissue Adhesions
Cell Transformation, Neoplastic
Lung Neoplasms
Sarcoma
Adenocarcinoma

Pathways

Angiogenesis
Cell Proliferation
Notch Signaling Pathway
Cell Differentiation
Sprouting Angiogenesis
Pathogenesis
Cell Development
Cell Cycle
Cell Growth
Localization
Endothelial Cell Proliferation
Cell Migration
Vasculogenesis

Tube Formation
Neurogenesis
Cell Fate Determination
Cell Activation
Lateral Inhibition
Regeneration
T Cell Differentiation

PTMs

Phosphorylation
Cleavage
Glycosylation

Acetylation
Deacetylation
Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dll4

References

PMID: 10837024 by Shutter J.R., et al. Dll4, a novel Notch ligand expressed in arterial endothelium.

PMID: 11134954 by Yoneya T., et al. Molecular cloning of Delta-4, a new mouse and human Notch ligand.