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- Table of Contents
Facts about Delta-like protein 3.
Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). .
Human | |
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Gene Name: | DLL3 |
Uniprot: | Q9NYJ7 |
Entrez: | 10683 |
Belongs to: |
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No superfamily |
delta (Drosophila)-like 3; Delta3; delta-like 3 (Drosophila); delta-like protein 3; DLL3; Drosophila Delta homolog 3; Pudgy; SCDO1; SCDO1delta3
Mass (kDA):
64.618 kDA
Human | |
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Location: | 19q13.2 |
Sequence: | 19; NC_000019.10 (39498947..39508469) |
Membrane; Single-pass type I membrane protein.
PMID: 10742114 by Bulman M.P., et al. Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis.
PMID: 18485326 by Cornier A.S., et al. Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho- Levin syndrome.